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Rehfeld A, Mendoza N, Ausejo R, et al. Bisphenol A Diglycidyl Ether (BADGE) and Progesterone Do Not Induce Ca. Front Physiol. 2020;11:785doi: 10.3389/fphys.2020.00785.
Rehfeld, A., Mendoza, N., Ausejo, R., & Skakkebæk, N. E. (2020). Bisphenol A Diglycidyl Ether (BADGE) and Progesterone Do Not Induce Ca. Frontiers in physiology, 11785. https://doi.org/10.3389/fphys.2020.00785
Rehfeld, Anders, et al. "Bisphenol A Diglycidyl Ether (BADGE) and Progesterone Do Not Induce Ca." Frontiers in physiology vol. 11 (2020): 785. doi: https://doi.org/10.3389/fphys.2020.00785
Rehfeld A, Mendoza N, Ausejo R, Skakkebæk NE. Bisphenol A Diglycidyl Ether (BADGE) and Progesterone Do Not Induce Ca. Front Physiol. 2020 Jul 07;11:785. doi: 10.3389/fphys.2020.00785. eCollection 2020. PMID: 32774306; PMCID: PMC7381341.
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Front Physiol. 2020 Jul 07;11:785. doi: 10.3389/fphys.2020.00785. eCollection 2020.

Bisphenol A Diglycidyl Ether (BADGE) and Progesterone Do Not Induce Ca.

Frontiers in physiology

Anders Rehfeld, Noelia Mendoza, Raquel Ausejo, Niels Erik Skakkebæk

Affiliations

  1. Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
  2. International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  3. Department of Research and Development, Magapor SL, Zaragoza, Spain.

PMID: 32774306 PMCID: PMC7381341 DOI: 10.3389/fphys.2020.00785

Abstract

AIM: Exposure of boar sperm cells to Bisphenol A diglycidyl ether (BADGE) has been shown to lead to reproductive failure in sows, however, the mode of action is unknown. As we have recently shown that BADGE can interfere with Ca

METHODS: Direct effects of BADGE and the endogenous ligand of human CatSper, progesterone, on Ca

RESULTS: The exact same solutions of BADGE and progesterone induced transient biphasic Ca

CONCLUSION: BADGE and progesterone failed to induce Ca

Copyright © 2020 Rehfeld, Mendoza, Ausejo and Skakkebæk.

Keywords: CatSper; Endocrine disruption; bisphenol; boar sperm; fertility

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