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Front Pediatr. 2020 Jul 22;8:355. doi: 10.3389/fped.2020.00355. eCollection 2020.

Biomarkers for the Discrimination of Acute Kawasaki Disease From Infections in Childhood.

Frontiers in pediatrics

Judith Zandstra, Annemarie van de Geer, Michael W T Tanck, Diana van Stijn-Bringas Dimitriades, Cathelijn E M Aarts, Sanne M Dietz, Robin van Bruggen, Nina A Schweintzger, Werner Zenz, Marieke Emonts, Dace Zavadska, Marko Pokorn, Effua Usuf, Henriette A Moll, Luregn J Schlapbach, Enitan D Carrol, Stephane Paulus, Maria Tsolia, Colin Fink, Shunmay Yeung, Chisato Shimizu, Adriana Tremoulet, Rachel Galassini, Victoria J Wright, Federico Martinón-Torres, Jethro Herberg, Jane Burns, Michael Levin, Taco W Kuijpers,

Affiliations

  1. Sanquin Research and Landsteiner Laboratory, Department of Immunopathology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands.
  2. Sanquin Research and Landsteiner Laboratory, Department of Blood Cell Research, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands.
  3. Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
  4. Department of Pediatric Immunology, Rheumatology and Infectious Diseases, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
  5. Department of General Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
  6. Pediatric Infectious Diseases and Immunology Department, Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.
  7. Department of Pediatrics, Riga Stradins University, Riga, Latvia.
  8. Department of Infectious Diseases, University Medical Centre Ljubljana, Ljubljana, Slovenia.
  9. Medical Research Council Unit the Gambia (MRCG) at LSHTM, Serrekunda, Gambia.
  10. Department of General Pediatrics, Erasmus MC-Sophia Children's Hospital, Rotterdam, Netherlands.
  11. Pediatric Intensive Care Unit, Lady Cilento Children's Hospital, Pediatric Critical Care Research Group, Brisbane, QLD, Australia.
  12. Department of Clinical Infection, Microbiology and Immunology, University of Liverpool Institute of Infection and Global Health, Liverpool, United Kingdom.
  13. Second Department of Pediatrics, P. & A. Kyriakou Children's Hospital, National and Kapodistrian University of Athens, Athens, Greece.
  14. Micropathology Ltd., University of Warwick, Warwick, United Kingdom.
  15. Department of Clinical Research, Faculty of Infectious and Tropical Disease, London School of Hygiene and Tropical Medicine, London, United Kingdom.
  16. Section of Paediatric Infectious Diseases, Department of Infectious Disease, Imperial College London, London, United Kingdom.
  17. Kawasaki Disease Research Center, Rady's Children's Hospital-San Diego, University of California, San Diego, San Diego, CA, United States.
  18. Translational Pediatrics and Infectious Diseases, Hospital Clínico Universitario de Santiago, University of Santiago, Santiago de Compostela, Spain.

PMID: 32775314 PMCID: PMC7388698 DOI: 10.3389/fped.2020.00355

[No abstract available.]

Copyright © 2020 Zandstra, van de Geer, Tanck, van Stijn-Bringas Dimitriades, Aarts, Dietz, van Bruggen, Schweintzger, Zenz, Emonts, Zavadska, Pokorn, Usuf, Moll, Schlapbach, Carrol, Paulus, Tsolia, Fink, Yeung, Shimizu, Tremoulet, Galassini, Wright, Martinón-Torres, Herberg, Burns, Levin, Kuijpers, EUCLIDS Consortium, PERFORM Consortium and UK Kawasaki Disease Genetics Study Network.

Keywords: bacterial infection; biomarker; coronary aneurysm; infectious disease; kawasaki disease; vasculitis; viral infection

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