Display options
Cite
Cherkani-Hassani A, Ghanname I, Zinedine A, et al. Ochratoxin a in breast milk in Morocco: the affecting dietary habits of the lactating mothers and the degree of exposure of newborns "CONTAMILK study". Drug Chem Toxicol. 2020;1-7doi: 10.1080/01480545.2020.1808669.
Cherkani-Hassani, A., Ghanname, I., Zinedine, A., Sefrioui, H., Qmichou, Z., & Mouane, N. (2020). Ochratoxin a in breast milk in Morocco: the affecting dietary habits of the lactating mothers and the degree of exposure of newborns "CONTAMILK study". Drug and chemical toxicology, 1-7. https://doi.org/10.1080/01480545.2020.1808669
Cherkani-Hassani, Abha, et al. "Ochratoxin a in breast milk in Morocco: the affecting dietary habits of the lactating mothers and the degree of exposure of newborns "CONTAMILK study"." Drug and chemical toxicology vol. (2020): 1-7. doi: https://doi.org/10.1080/01480545.2020.1808669
Cherkani-Hassani A, Ghanname I, Zinedine A, Sefrioui H, Qmichou Z, Mouane N. Ochratoxin a in breast milk in Morocco: the affecting dietary habits of the lactating mothers and the degree of exposure of newborns "CONTAMILK study". Drug Chem Toxicol. 2020 Aug 24;1-7. doi: 10.1080/01480545.2020.1808669. Epub 2020 Aug 24. PMID: 32838562.
Copy Download .nbib Format: NLM
Share it on

Drug Chem Toxicol. 2020 Aug 24;1-7. doi: 10.1080/01480545.2020.1808669. Epub 2020 Aug 24.

Ochratoxin a in breast milk in Morocco: the affecting dietary habits of the lactating mothers and the degree of exposure of newborns "CONTAMILK study".

Drug and chemical toxicology

Abha Cherkani-Hassani, Imane Ghanname, Abdellah Zinedine, Hassan Sefrioui, Zineb Qmichou, Nezha Mouane

Affiliations

  1. Unit of training and research in Nutrition and Food Sciences, Faculty of Medicine and Pharmacy, University Mohammed V, Rabat, Morocco.
  2. Faculty of Health Sciences, International University of Casablanca, Casablanca, Morocco.
  3. Faculty of Sciences, BIOMARE Laboratory, Applied Microbiology and Biotechnologies, Chouaib Doukkali University, El Jadida, Morocco.
  4. Moroccan Foundation for Advanced Science, Innovation & Research (MAScIR)-Medical Biotechnology Center, Rabat, Morocco.
  5. Department of Pediatric Hepatology Gastroenterology and Nutrition, P III, Children's Hospital of Rabat, Rabat, Morocco.

PMID: 32838562 DOI: 10.1080/01480545.2020.1808669

Abstract

The aim of the present study is to evaluate the level of contamination of breast milk (BM) by ochratoxin A, among Moroccan lactating mothers in the city of Rabat, and to identify the associated factors of exposure, also to estimate the degree of exposure of the breastfeed infant. The analysis of ochratoxin A (OTA) was accomplished by ELISA method on 82 colostrum samples. OTA was detectable (>0.08 ng/mL) in 55% of samples with a maximum concentration of 10.04 ng/mL, and the levels exceeded 0.5 ng /mL in 50 % of the samples. In addition, several factors and dietary habits affect significantly the level of OTA in the analyzed samples of breast milk including, the consumption of industrial dairy products, the frequency of consumption of canned foods, dried fruits and legumes, also the period of breast milk collection. Besides, OTA was higher than the tolerable daily intake for 49% newborns. However, these results need to be confirmed by multicenter studies to more broadly estimate the levels of exposition of Moroccan population to OTA. Furthermore, awareness campaigns are recommended to inform the public, especially pregnant women and lactating women about appropriate preventive measures to limit exposure to this mycotoxin.

Keywords: Morocco; Ochratoxin A; associated factors; breast milk; daily intake

Publication Types