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Graff JT, Cortez AR, Dhar VK, et al. Perioperative thrombelastography serves as an important assessment tool of transfusion requirements during liver transplantation. Surg Open Sci. 2020;2(2):70-74doi: 10.1016/j.sopen.2019.12.004.
Graff, J. T., Cortez, A. R., Dhar, V. K., Wakefield, C., Cuffy, M. C., Shah, S. A., & Goodman, M. D. (2020). Perioperative thrombelastography serves as an important assessment tool of transfusion requirements during liver transplantation. Surgery open science, 2(2), 70-74. https://doi.org/10.1016/j.sopen.2019.12.004
Graff, Justin T, et al. "Perioperative thrombelastography serves as an important assessment tool of transfusion requirements during liver transplantation." Surgery open science vol. 2,2 (2020): 70-74. doi: https://doi.org/10.1016/j.sopen.2019.12.004
Graff JT, Cortez AR, Dhar VK, Wakefield C, Cuffy MC, Shah SA, Goodman MD. Perioperative thrombelastography serves as an important assessment tool of transfusion requirements during liver transplantation. Surg Open Sci. 2020 Jan 23;2(2):70-74. doi: 10.1016/j.sopen.2019.12.004. eCollection 2020 Apr. PMID: 32754709; PMCID: PMC7391895.
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Surg Open Sci. 2020 Jan 23;2(2):70-74. doi: 10.1016/j.sopen.2019.12.004. eCollection 2020 Apr.

Perioperative thrombelastography serves as an important assessment tool of transfusion requirements during liver transplantation.

Surgery open science

Justin T Graff, Alexander R Cortez, Vikrom K Dhar, Connor Wakefield, Madison C Cuffy, Shimul A Shah, Michael D Goodman

Affiliations

  1. Cincinnati Research on Outcomes and Safety in Surgery (CROSS), Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, OH.

PMID: 32754709 PMCID: PMC7391895 DOI: 10.1016/j.sopen.2019.12.004

Abstract

BACKGROUND: Thrombelastography has become increasingly used in liver transplantation. The implications of thrombelastography at various stages of liver transplantation, however, remain poorly understood. Our goal was to examine thrombelastography-based coagulopathy profiles in liver transplantation and determine whether preoperative thrombelastography is predictive of transfusion requirements perioperatively.

METHODS: A retrospective review of 364 liver transplantations from January 2013 to May 2017 at a single institution was performed. Patients were categorized as hypocoagulable or nonhypocoagulable based on their preoperative thrombelastography profile. The primary outcome was intraoperative transfusion requirements.

RESULTS: Of patients undergoing liver transplantation, 47% (

CONCLUSION: Coagulation abnormalities are common among liver transplantation patients and can be identified using thrombelastography. Identification of a patient's coagulation state preoperatively aids in guiding transfusion during liver transplantation. This work serves to better direct clinicians during major surgery to improve perioperative resource utilization. Future prospective work should aim to identify specific thrombelastography values that may predict transfusion requirements.

© 2020 The Authors.

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