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Hedermann G, Hedley PL, Bækvad-Hansen M, et al. Danish premature birth rates during the COVID-19 lockdown. Arch Dis Child Fetal Neonatal Ed. 2020;106(1):93-95doi: 10.1136/archdischild-2020-319990.
Hedermann, G., Hedley, P. L., Bækvad-Hansen, M., Hjalgrim, H., Rostgaard, K., Poorisrisak, P., Breindahl, M., Melbye, M., Hougaard, D. M., Christiansen, M., & Lausten-Thomsen, U. (2021). Danish premature birth rates during the COVID-19 lockdown. Archives of disease in childhood. Fetal and neonatal edition, 106(1), 93-95. https://doi.org/10.1136/archdischild-2020-319990
Hedermann, Gitte, et al. "Danish premature birth rates during the COVID-19 lockdown." Archives of disease in childhood. Fetal and neonatal edition vol. 106,1 (2021): 93-95. doi: https://doi.org/10.1136/archdischild-2020-319990
Hedermann G, Hedley PL, Bækvad-Hansen M, Hjalgrim H, Rostgaard K, Poorisrisak P, Breindahl M, Melbye M, Hougaard DM, Christiansen M, Lausten-Thomsen U. Danish premature birth rates during the COVID-19 lockdown. Arch Dis Child Fetal Neonatal Ed. 2021 Jan;106(1):93-95. doi: 10.1136/archdischild-2020-319990. Epub 2020 Aug 11. PMID: 32788391; PMCID: PMC7421710.
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Arch Dis Child Fetal Neonatal Ed. 2021 Jan;106(1):93-95. doi: 10.1136/archdischild-2020-319990. Epub 2020 Aug 11.

Danish premature birth rates during the COVID-19 lockdown.

Archives of disease in childhood. Fetal and neonatal edition

Gitte Hedermann, Paula Louise Hedley, Marie Bækvad-Hansen, Henrik Hjalgrim, Klaus Rostgaard, Porntiva Poorisrisak, Morten Breindahl, Mads Melbye, David M Hougaard, Michael Christiansen, Ulrik Lausten-Thomsen

Affiliations

  1. Department for Congenital Disorders, Danish National Biobank and Biomarkers, Statens Serum Institut, Copenhagen, Denmark.
  2. Danish Center for Neonatal Screening, Statens Serum Institut, Copenhagen, Denmark.
  3. Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
  4. Department of Haematology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
  5. Department of Neonatology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
  6. Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  7. Department of Medicine, Stanford University School of Medicine, Stanford, CA, US.
  8. Department for Congenital Disorders, Danish National Biobank and Biomarkers, Statens Serum Institut, Copenhagen, Denmark [email protected] [email protected].
  9. Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
  10. Department of Neonatology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark [email protected] [email protected].

PMID: 32788391 PMCID: PMC7421710 DOI: 10.1136/archdischild-2020-319990

Abstract

To explore the impact of COVID-19 lockdown on premature birth rates in Denmark, a nationwide register-based prevalence proportion study was conducted on all 31 180 live singleton infants born in Denmark between 12 March and 14 April during 2015-2020.The distribution of gestational ages (GAs) was significantly different (p=0.004) during the lockdown period compared with the previous 5 years and was driven by a significantly lower rate of extremely premature children during the lockdown compared with the corresponding mean rate for the same dates in the previous years (OR 0.09, 95% CI 0.01 to 0.40, p<0.001). No significant difference between the lockdown and previous years was found for other GA categories.The reasons for this decrease are unclear. However, the lockdown has provided a unique opportunity to examine possible factors related to prematurity. Identification of possible causal mechanisms might stimulate changes in clinical practice.

© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Keywords: epidemiology; neonatology

Conflict of interest statement

Competing interests: MB has a patent (NeoHelp) with royalties paid.

References

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