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EJNMMI Res. 2020 Aug 28;10(1):100. doi: 10.1186/s13550-020-00678-2.

Initial evaluation of (4S)-4-(3-[.

EJNMMI research

Sonya Y Park, Camila Mosci, Meena Kumar, Mirwais Wardak, Norman Koglin, Santiago Bullich, Andre Mueller, Mathias Berndt, Andrew W Stephens, Frederick T Chin, Sanjiv S Gambhir, Erik S Mittra

Affiliations

  1. Department of Radiology, Division of Nuclear Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
  2. Molecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University School of Medicine, Stanford, CA, USA.
  3. Bayer Pharma AG, Berlin, Germany.
  4. Life Molecular Imaging GmbH, Berlin, Germany.
  5. Department of Bioengineering, Stanford University, Stanford, CA, USA.
  6. Department of Materials Science & Engineering, Stanford University, Stanford, CA, USA.
  7. Bio-X Program, Stanford University, Stanford, CA, USA.
  8. Molecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University School of Medicine, Stanford, CA, USA. [email protected].
  9. Department of Diagnostic Radiology, Division of Nuclear Medicine & Molecular Imaging, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Mail Code L340, Portland, OR, 97239, USA. [email protected].

PMID: 32857284 PMCID: PMC7455665 DOI: 10.1186/s13550-020-00678-2

Abstract

PURPOSE: (4S)-4-(3-[

METHODS: A total of 15 subjects with HNC (n = 5), CRC (n = 5), or NHL (n = 5) were recruited (mean age 66.2 years, range 44-87 years). 301.4 ± 28.1 MBq (8.1 ± 0.8 mCi) of [

RESULTS: [

CONCLUSIONS: [

Keywords: Colorectal cancer; Glutamate; Head and neck cancer; Lymphoma; PET/CT; Positron emission tomography; [18F]FSPG; xC− transporter

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