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Kirubhanand C, Selvaraj J, Rekha UV, et al. Molecular docking data of piperine with Bax, Caspase 3, Cox 2 and Caspase 9. Bioinformation. 2020;16(6):458-461doi: 10.6026/97320630016458.
Kirubhanand, C., Selvaraj, J., Rekha, U. V., Vishnupriya, V., Nalini, D., Mohan, S. K., Vijayalakshmi, P., Rajalakshmi, M., & Ponnulakshmi, R. (2020). Molecular docking data of piperine with Bax, Caspase 3, Cox 2 and Caspase 9. Bioinformation, 16(6), 458-461. https://doi.org/10.6026/97320630016458
Kirubhanand, Chandrasekaran, et al. "Molecular docking data of piperine with Bax, Caspase 3, Cox 2 and Caspase 9." Bioinformation vol. 16,6 (2020): 458-461. doi: https://doi.org/10.6026/97320630016458
Kirubhanand C, Selvaraj J, Rekha UV, Vishnupriya V, Nalini D, Mohan SK, Vijayalakshmi P, Rajalakshmi M, Ponnulakshmi R. Molecular docking data of piperine with Bax, Caspase 3, Cox 2 and Caspase 9. Bioinformation. 2020 Jun 30;16(6):458-461. doi: 10.6026/97320630016458. eCollection 2020. PMID: 32884209; PMCID: PMC7452745.
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Bioinformation. 2020 Jun 30;16(6):458-461. doi: 10.6026/97320630016458. eCollection 2020.

Molecular docking data of piperine with Bax, Caspase 3, Cox 2 and Caspase 9.

Bioinformation

Chandrasekaran Kirubhanand, Jayaraman Selvaraj, Umapathy Vidhya Rekha, Veeraraghavan Vishnupriya, Devarajan Nalini, Surapaneni Krishna Mohan, Periyasamy Vijayalakshmi, Manikkam Rajalakshmi, Rajagopal Ponnulakshmi

Affiliations

  1. Department of Anatomy, All India Institute of Medical Sciences, Nagpur, India.
  2. Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, India.
  3. Department of Public Health Dentistry, Sree Balaji Dental College and Hospital, Pallikaranai, Chennai-600 100, India.
  4. Central Research Laboratory, Meenakshmi Ammal Dental College, Meenakshi Academy of Higher Education and Research (Deemed to be University), Chennai-600 095, India.
  5. Panimalar Medical College Hospital and Research Institute, Varadharajapuram, Poonamallee, Chennai-600 123, Tamil Nadu, India.
  6. DBT-BIF Centre, PG and Research Department of Biotechnology and Bioinformatics, Holy Cross College (Autonomous), Trichy, Tamilnadu, India.
  7. Central Research Laboratory, Meenakshi Academy of Higher Education and Research (Deemed to be University), West K. K. Nagar, Chennai-600 078, India.

PMID: 32884209 PMCID: PMC7452745 DOI: 10.6026/97320630016458

Abstract

Several apoptotic signalling proteins such as Bax, Caspase 3, Cox 2 and Caspase 9 are known to be associated with colorectal cancer (CRC). It is of interest to study the interaction of these proteins with piperine a known drug candidate. We document the binding energy, hydrogen bond interaction and hydrophobic interaction between the piperine and apoptotic proteins for further consideration.

© 2020 Biomedical Informatics.

Keywords: Bax; Caspase 3; Caspase 9; Cox 2; Piperine; molecular docking

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