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Toxicol Res (Camb). 2020 Jul 01;9(4):331-345. doi: 10.1093/toxres/tfaa044. eCollection 2020 Jul.

Global nature of airborne particle toxicity and health effects: a focus on megacities, wildfires, dust storms and residential biomass burning.

Toxicology research

Frank J Kelly, Julia C Fussell

Affiliations

  1. NIHR Health Protection Research Unit in Environmental Exposures and Health, School of Public Health, Sir Michael Uren Building, Imperial College London, White City Campus, 80-92 Wood Lane, London W12 0BZ, UK.

PMID: 32905302 PMCID: PMC7467248 DOI: 10.1093/toxres/tfaa044

Abstract

Since air pollutants are difficult and expensive to control, a strong scientific underpinning to policies is needed to guide mitigation aimed at reducing the current burden on public health. Much of the evidence concerning hazard identification and risk quantification related to air pollution comes from epidemiological studies. This must be reinforced with mechanistic confirmation to infer causality. In this review we focus on data generated from four contrasting sources of particulate air pollution that result in high population exposures and thus where there remains an unmet need to protect health: urban air pollution in developing megacities, household biomass combustion, wildfires and desert dust storms. Taking each in turn, appropriate measures to protect populations will involve advocating smart cities and addressing economic and behavioural barriers to sustained adoption of clean stoves and fuels. Like all natural hazards, wildfires and dust storms are a feature of the landscape that cannot be removed. However, many efforts from emission containment (land/fire management practices), exposure avoidance and identifying susceptible populations can be taken to prepare for air pollution episodes and ensure people are out of harm's way when conditions are life-threatening. Communities residing in areas affected by unhealthy concentrations of any airborne particles will benefit from optimum communication via public awareness campaigns, designed to empower people to modify behaviour in a way that improves their health as well as the quality of the air they breathe.

© The Author(s) 2020. Published by Oxford University Press. All rights reserved. For Permissions, please email: [email protected].

Keywords: desert dust; epidemiology; household air pollution; megacities; particulate matter; toxicology; wildfires

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