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D'Antonio M, D'Antonio-Chronowska A, Frazer KA. Revealing Instability: Genetic Variation Underlies Variability in mESC Pluripotency. Cell Stem Cell. 2020;27(3):347-349doi: 10.1016/j.stem.2020.08.012.
D'Antonio, M., D'Antonio-Chronowska, A., & Frazer, K. A. (2020). Revealing Instability: Genetic Variation Underlies Variability in mESC Pluripotency. Cell stem cell, 27(3), 347-349. https://doi.org/10.1016/j.stem.2020.08.012
D'Antonio, Matteo, et al. "Revealing Instability: Genetic Variation Underlies Variability in mESC Pluripotency." Cell stem cell vol. 27,3 (2020): 347-349. doi: https://doi.org/10.1016/j.stem.2020.08.012
D'Antonio M, D'Antonio-Chronowska A, Frazer KA. Revealing Instability: Genetic Variation Underlies Variability in mESC Pluripotency. Cell Stem Cell. 2020 Sep 03;27(3):347-349. doi: 10.1016/j.stem.2020.08.012. PMID: 32888420.
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Cell Stem Cell. 2020 Sep 03;27(3):347-349. doi: 10.1016/j.stem.2020.08.012.

Revealing Instability: Genetic Variation Underlies Variability in mESC Pluripotency.

Cell stem cell

Matteo D'Antonio, Agnieszka D'Antonio-Chronowska, Kelly A Frazer

Affiliations

  1. Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.
  2. Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: [email protected].

PMID: 32888420 DOI: 10.1016/j.stem.2020.08.012

Abstract

mESCs can self-renew indefinitely in vitro. However, depending on culture conditions some strains are more unstable than others. In this issue of Cell Stem Cell, Skelly et al. (2020) and Ortmann et al. (2020) shed light into the role genetic variation plays in control of ground state pluripotency.

Copyright © 2020 Elsevier Inc. All rights reserved.

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