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Biringer RG. A Review of Prostanoid Receptors: Expression, Characterization, Regulation, and Mechanism of Action. J Cell Commun Signal. 2020;15(2):155-184doi: 10.1007/s12079-020-00585-0.
Biringer, R. G. (2021). A Review of Prostanoid Receptors: Expression, Characterization, Regulation, and Mechanism of Action. Journal of cell communication and signaling, 15(2), 155-184. https://doi.org/10.1007/s12079-020-00585-0
Biringer, Roger G. "A Review of Prostanoid Receptors: Expression, Characterization, Regulation, and Mechanism of Action." Journal of cell communication and signaling vol. 15,2 (2021): 155-184. doi: https://doi.org/10.1007/s12079-020-00585-0
Biringer RG. A Review of Prostanoid Receptors: Expression, Characterization, Regulation, and Mechanism of Action. J Cell Commun Signal. 2021 Jun;15(2):155-184. doi: 10.1007/s12079-020-00585-0. Epub 2020 Sep 24. PMID: 32970276; PMCID: PMC7991060.
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J Cell Commun Signal. 2021 Jun;15(2):155-184. doi: 10.1007/s12079-020-00585-0. Epub 2020 Sep 24.

A Review of Prostanoid Receptors: Expression, Characterization, Regulation, and Mechanism of Action.

Journal of cell communication and signaling

Roger G Biringer

Affiliations

  1. College of Osteopathic Medicine, Lake Erie College of Osteopathic Medicine, 5000 Lakewood Ranch Blvd, Bradenton, FL, 34211, USA. [email protected].

PMID: 32970276 PMCID: PMC7991060 DOI: 10.1007/s12079-020-00585-0

Abstract

Prostaglandin signaling controls a wide range of biological processes from blood pressure homeostasis to inflammation and resolution thereof to the perception of pain to cell survival. Disruption of normal prostanoid signaling is implicated in numerous disease states. Prostaglandin signaling is facilitated by G-protein-coupled, prostanoid-specific receptors and the array of associated G-proteins. This review focuses on the expression, characterization, regulation, and mechanism of action of prostanoid receptors with particular emphasis on human isoforms.

Keywords: G-protein; eicosanoid; prostaglandin; prostanoid; receptor; signaling

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