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J Oral Microbiol. 2020 Jul 03;12(1):1788352. doi: 10.1080/20002297.2020.1788352.

Mucus is more than just a physical barrier for trapping oral microorganisms.

Journal of oral microbiology

Ingar Olsen

Affiliations

  1. Department of Oral Biology, Faculty of Dentistry, University of Oslo, Oslo, Norway.

PMID: 32944151 PMCID: PMC7482763 DOI: 10.1080/20002297.2020.1788352

Abstract

Mucus is thought to serve as a protective coating on wet epithelial surfaces. Recent research has shown that glycans, which are branched sugar molecules found in mucin, a part of mucus, can prevent bacteria from communicating with each other and forming biofilms. This could hinder microbes from causing infections. The present editorial, focusing on a paper by Wheeler et al. [1], published in October 2019 in Nature Microbiology, describes how mucus can attenuate the virulence of

© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

Keywords: Candida albicans; Mucus; Pseudomonas aeruginosa; attenuation; biofilm; communication; glycans; mucins; streptococci; virulence

Conflict of interest statement

No potential conflict of interest was reported by the author.

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