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Infect Dis (Auckl). 2020 Aug 28;13:1178633720952077. doi: 10.1177/1178633720952077. eCollection 2020.

Bacterial Etiology of Wound Exudates in Tertiary Care Cancer Patients and Antibiogram of the Isolates.

Infectious diseases

Kiran Duwadi, Sujan Khadka, Sanjib Adhikari, Sanjeep Sapkota, Pabitra Shrestha

Affiliations

  1. Department of Microbiology, Birendra Multiple Campus, Tribhuvan University, Bharatpur, Chitwan, Nepal.
  2. State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China.
  3. University of Chinese Academy of Sciences, Beijing, China.
  4. State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.

PMID: 32922030 PMCID: PMC7457650 DOI: 10.1177/1178633720952077

Abstract

INTRODUCTION: Patients with malignancies frequently develop infections as a result of surgical procedures and fungating wounds leading to pus formation. This cross-sectional study was conducted to explore the bacteriological spectra of infections of various cancer sites and their antibiotic sensitivity patterns among the patients visiting minor operation theatre (OT) of B.P. Koirala Memorial Cancer Hospital (BPKMCH), Chitwan, Nepal.

METHODS: Over a period of 3 months from September to November 2018, a total of 183 wound exudates and pus samples were collected and analyzed by standard microbiological procedures. Isolates were identified based on the colony characters, Gram staining and an array of biochemical tests. Antibiotic susceptibility testing was performed by Kirby-Bauer disc diffusion technique according to criteria set by CLSI, 2016. Methicillin resistance in

RESULTS: Out of the 183 samples, 149 (81.4%) were culture positive. Among 13 different isolates identified,

CONCLUSION: This study suggests that patients with malignancies harbor pathogenic bacteria; therefore, prudent use of antibiotics is essential to prevent the emergence of MDR pathogens.

© The Author(s) 2020.

Keywords: Cancer; MDR; MRSA; cancer treatment; infection

Conflict of interest statement

Declaration of conflicting interests:The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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