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Vergot K, Pockar S, Umek L, et al. Clinical Features of Acute Anterior Uveitis with Complicated Course in a Slovenian Patient Population. J Ophthalmol. 2020;2020:6079146doi: 10.1155/2020/6079146.
Vergot, K., Pockar, S., Umek, L., & Vidovic Valentincic, N. (2020). Clinical Features of Acute Anterior Uveitis with Complicated Course in a Slovenian Patient Population. Journal of ophthalmology, 20206079146. https://doi.org/10.1155/2020/6079146
Vergot, Katarina, et al. "Clinical Features of Acute Anterior Uveitis with Complicated Course in a Slovenian Patient Population." Journal of ophthalmology vol. 2020 (2020): 6079146. doi: https://doi.org/10.1155/2020/6079146
Vergot K, Pockar S, Umek L, Vidovic Valentincic N. Clinical Features of Acute Anterior Uveitis with Complicated Course in a Slovenian Patient Population. J Ophthalmol. 2020 Sep 19;2020:6079146. doi: 10.1155/2020/6079146. eCollection 2020. PMID: 33014440; PMCID: PMC7520672.
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J Ophthalmol. 2020 Sep 19;2020:6079146. doi: 10.1155/2020/6079146. eCollection 2020.

Clinical Features of Acute Anterior Uveitis with Complicated Course in a Slovenian Patient Population.

Journal of ophthalmology

Katarina Vergot, Sasa Pockar, Lan Umek, Natasa Vidovic Valentincic

Affiliations

  1. Eye Hospital, University Clinical Center, Ljubljana, Slovenia.
  2. Faculty of Administration, University of Ljubljana, Ljubljana, Slovenia.
  3. Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.

PMID: 33014440 PMCID: PMC7520672 DOI: 10.1155/2020/6079146

Abstract

PURPOSE: To report on patients who needed hospitalization due to acute anterior uveitis (AAU) and within this group to compare clinical features and outcomes of treatment of HLA-B27+ and HLA-B27- AAU in the population of Slovenian patients.

METHODS: Retrospective study of hospitalized patients with AAU in the last 39 months at the Eye Hospital in Ljubljana. The data of AAU patients were retroactively studied and compared on the basis of HLA-B27 antigen presence: visual acuity upon admission, visual outcome, the presence of hypopyon, fibrinous reaction, posterior iris synechiae, and complications, such as elevated intraocular pressure, cataract, and cystoid macular edema (CME). We compared the investigations in the diagnostic process, the associated systemic disease, and the treatment administered. Statistical analyses included Student's

RESULTS: A total of 37 hospitalized patients with AAU were included. HLA-B27 antigen was detected in 73% of patients. In the HLA-B27+ group, women were more commonly affected, while the males were more affected in the HLA-B27- group. The occurrence of fibrin was significantly more common in HLA-B27+ patients, as well as hypopyon and posterior synechiae; only fibrin reached the statistical significance (

CONCLUSION: Almost ¾ of AAU patients that required hospitalization were HLA-B27+. In this group, disease was more severe, more frequently associated with ocular complications and systemic disease, but final visual acuity was the same in both groups. HLA-B27 typing has no prognostic value in our group of complicated AAU patients, but it eases the decision about necessary diagnostics and treatment.

Copyright © 2020 Katarina Vergot et al.

Conflict of interest statement

The authors declare that there are no conflicts of interest regarding the publication of this paper.

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