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3 Biotech. 2020 Oct;10(10):445. doi: 10.1007/s13205-020-02435-7. Epub 2020 Sep 19.

NF-κB signaling induces inductive expression of the downstream molecules and IgD gene in the freshwater carp, .

3 Biotech

Rajanya Banerjee, Mrinal Samanta, Surajit Das

Affiliations

  1. Laboratory of Environmental Microbiology and Ecology (LEnME), Department of Life Science, National Institute of Technology, Rourkela, Odisha 769008 India.
  2. Fish Health Management Division, ICAR-Central Institute of Freshwater Aquaculture, Kausalyaganga, Bhubaneswar, Odisha 751002 India.

PMID: 33014688 PMCID: PMC7502101 DOI: 10.1007/s13205-020-02435-7

Abstract

Toll-like receptors (TLRs) in innate immune system act as primary sensors in detecting the microbial components and activate their signaling cascades to induce NF-κB (nuclear factor NF-κB) towards the augmentation of immunoglobulin (Ig) synthesis. To gain insights into the efficacy of NF-κB pathway in immunoglobulin D (IgD) synthesis in the Indian Major Carp

© King Abdulaziz City for Science and Technology 2020.

Keywords: BAFF; Catla catla; IgD; Immunoglobulin; NEMO; NF-κb; TRAF3

Conflict of interest statement

Conflict of interestThe authors declare no conflict of interest.

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