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JCO Precis Oncol. 2020 Sep 16;4. doi: 10.1200/PO.19.00400. eCollection 2020.

Undetectable .

JCO precision oncology

Mohamed Bouchahda, Raphael Saffroy, Abdoulaye Karaboué, Jocelyne Hamelin, Pasquale Innominato, Faouzi Saliba, Francis Lévi, Nelly Bosselut, Antoinette Lemoine

Affiliations

  1. Medical Oncology Department, Paul Brousse Hospital, Villejuif, France.
  2. Medical Oncology Unit, Clinique du Mousseau, Evry, France.
  3. Oncogenetics Department, Assistance Publique-Hôpitaux de Paris, Paul Brousse Hospital, Université Paris-Saclay, Villejuif, France.
  4. French National Institute for Health and Medical Research (INSERM), Unit 935, Villejuif, France.
  5. Medical Oncology Unit, Groupe Hospitalier Intercommunal Le Raincy-Montfermeil, Montfermeil, France.
  6. North Wales Cancer Centre, Ysbyty Gwynedd, Betsi Cadwaladr University Health Board, Bangor, United Kingdom.
  7. Cancer Chronotherapy Team, Cancer Research Centre, Division of Biomedical Sciences, Warwick Medical School, Coventry, United Kingdom.
  8. Centre Hépato Biliaire, Assistance Publique-Hôpitaux de Paris, Hôpital Paul Brousse, Villejuif, France.

PMID: 33015528 PMCID: PMC7529530 DOI: 10.1200/PO.19.00400

Abstract

PURPOSE: Combining cetuximab with chemotherapy provides clinical benefit to 60% of the patients with

MATERIALS AND METHODS: The occurrence of Kirsten rat sarcoma viral oncogene homolog (

RESULTS: Of 16 registered patients, 11 were male and five female. They were age 48 to 81 years, and they had unresectable metastatic adenocarcinoma from the colon (n = 11) or rectum (n = 5), with a median of two metastatic sites. They had received a median number of three previous chemotherapy protocols. Plasma genotyping identified

CONCLUSION: Patients with

© 2020 by American Society of Clinical Oncology.

Conflict of interest statement

The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated unless otherwise noted. Relationships are self-held unless noted. I

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