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Jang TS, Jung HD, Pan HM, et al. 3D printing of hydrogel composite systems: Recent advances in technology for tissue engineering. Int J Bioprint. 2018;4(1):126doi: 10.18063/IJB.v4i1.126.
Jang, T. S., Jung, H. D., Pan, H. M., Han, W. T., Chen, S., & Song, J. (2018). 3D printing of hydrogel composite systems: Recent advances in technology for tissue engineering. International journal of bioprinting, 4(1), 126. https://doi.org/10.18063/IJB.v4i1.126
Jang, Tae-Sik, et al. "3D printing of hydrogel composite systems: Recent advances in technology for tissue engineering." International journal of bioprinting vol. 4,1 (2018): 126. doi: https://doi.org/10.18063/IJB.v4i1.126
Jang TS, Jung HD, Pan HM, Han WT, Chen S, Song J. 3D printing of hydrogel composite systems: Recent advances in technology for tissue engineering. Int J Bioprint. 2018 Jan 19;4(1):126. doi: 10.18063/IJB.v4i1.126. eCollection 2018. PMID: 33102909; PMCID: PMC7582009.
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Int J Bioprint. 2018 Jan 19;4(1):126. doi: 10.18063/IJB.v4i1.126. eCollection 2018.

3D printing of hydrogel composite systems: Recent advances in technology for tissue engineering.

International journal of bioprinting

Tae-Sik Jang, Hyun-Do Jung, Houwen Matthew Pan, Win Tun Han, Shengyang Chen, Juha Song

Affiliations

  1. School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore.
  2. Liquid Processing & Casting Technology R&D Group, Korea Institute of Industrial Technology, Incheon, Republic of Korea.

PMID: 33102909 PMCID: PMC7582009 DOI: 10.18063/IJB.v4i1.126

Abstract

Three-dimensional (3D) printing of hydrogels is now an attractive area of research due to its capability to fabricate intricate, complex and highly customizable scaffold structures that can support cell adhesion and promote cell infiltration for tissue engineering. However, pure hydrogels alone lack the necessary mechanical stability and are too easily degraded to be used as printing ink. To overcome this problem, significant progress has been made in the 3D printing of hydrogel composites with improved mechanical performance and biofunctionality. Herein, we provide a brief overview of existing hydrogel composite 3D printing techniques including laser based-3D printing, nozzle based-3D printing, and inkjet printer based-3D printing systems. Based on the type of additives, we will discuss four main hydrogel composite systems in this review: polymer- or hydrogel-hydrogel composites, particle-reinforced hydrogel composites, fiber-reinforced hydrogel composites, and anisotropic filler-reinforced hydrogel composites. Additionally, several emerging potential applications of hydrogel composites in the field of tissue engineering and their accompanying challenges are discussed in parallel.

Copyright: © 2018 Jang T-S, et al.

Keywords: 3D printing; hydrogel composites; tissue engineering

Conflict of interest statement

No conflict of interest was reported by all authors. This research was supported by AcRF Tier 1 grant 2017- T1-001-246 (RG51/17) from Ministry of Education of Singapore, and Basic Science Research Pro

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