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Frydensberg VS, Johansen JB, Möller S, et al. Anxiety and depression symptoms in Danish patients with an implantable cardioverter-defibrillator: prevalence and association with indication and sex up to 2 years of follow-up (data from the national DEFIB-WOMEN study). Europace. 2020;22(12):1830-1840doi: 10.1093/europace/euaa176.
Frydensberg, V. S., Johansen, J. B., Möller, S., Riahi, S., Wehberg, S., Haarbo, J., Philbert, B. T., Jørgensen, O. D., Larsen, M. L., Nielsen, J. C., & Pedersen, S. S. (2020). Anxiety and depression symptoms in Danish patients with an implantable cardioverter-defibrillator: prevalence and association with indication and sex up to 2 years of follow-up (data from the national DEFIB-WOMEN study). Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 22(12), 1830-1840. https://doi.org/10.1093/europace/euaa176
Frydensberg, Vivi Skibdal, et al. "Anxiety and depression symptoms in Danish patients with an implantable cardioverter-defibrillator: prevalence and association with indication and sex up to 2 years of follow-up (data from the national DEFIB-WOMEN study)." Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology vol. 22,12 (2020): 1830-1840. doi: https://doi.org/10.1093/europace/euaa176
Frydensberg VS, Johansen JB, Möller S, Riahi S, Wehberg S, Haarbo J, Philbert BT, Jørgensen OD, Larsen ML, Nielsen JC, Pedersen SS. Anxiety and depression symptoms in Danish patients with an implantable cardioverter-defibrillator: prevalence and association with indication and sex up to 2 years of follow-up (data from the national DEFIB-WOMEN study). Europace. 2020 Dec 23;22(12):1830-1840. doi: 10.1093/europace/euaa176. PMID: 33106878.
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Europace. 2020 Dec 23;22(12):1830-1840. doi: 10.1093/europace/euaa176.

Anxiety and depression symptoms in Danish patients with an implantable cardioverter-defibrillator: prevalence and association with indication and sex up to 2 years of follow-up (data from the national DEFIB-WOMEN study).

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

Vivi Skibdal Frydensberg, Jens Brock Johansen, Sören Möller, Sam Riahi, Sonja Wehberg, Jens Haarbo, Berit Thornvig Philbert, Ole Dan Jørgensen, Mogens Lytken Larsen, Jens Cosedis Nielsen, Susanne S Pedersen

Affiliations

  1. Department of Psychology, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark.
  2. Department of Cardiology, Odense University Hospital, Odense, Denmark.
  3. OPEN, Open Patient data Explorative Network, Odense University Hospital, Odense, Denmark.
  4. Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
  5. Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
  6. Research Unit for General Practice, Department of Public Health, University of Southern Denmark, Odense C, Denmark.
  7. Department of Cardiology, Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark.
  8. Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
  9. Department of Heart Lung & Vascular Surgery, Odense University Hospital, Odense, Denmark.
  10. Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.

PMID: 33106878 DOI: 10.1093/europace/euaa176

Abstract

AIMS: To investigate (i) the prevalence of anxiety and depression and (ii) the association between indication for implantable cardioverter-defibrillator (ICD) implantation and sex in relation to anxiety and depression up to 24 months' follow-up.

METHODS AND RESULTS: Patients with a first-time ICD, participating in the national, multi-centre, prospective DEFIB-WOMEN study (n = 1496; 18% women) completed the Hospital Anxiety and Depression Scale at baseline, 3, 6, 12, and 24 months. Data were analysed using linear mixed modelling for longitudinal data. Patients with a secondary prophylactic indication (SPI) had higher mean anxiety scores than patients with a primary prophylactic indication (PPI) at baseline, 3, and 12 months and higher mean depression scores at all-time points, except at 24 months. Women had higher mean anxiety scores as compared to men at all-time points; however, only higher mean depression scores at baseline. Overall, women with SPI had higher anxiety and depression symptom scores than men with SPI. Symptoms decreased over time in both women and men. From baseline to follow-up, the prevalence of anxiety (score ≥8) was highest in patients with SPI (13.3-20.2%) as compared to patients with PPI (range 10.0-14.7%). The prevalence of depression was stable over the follow-up period in both groups (range 8.5-11.1%).

CONCLUSION: Patients with a SPI reported higher anxiety and depression scores as compared to patients with PPI. Women reported higher anxiety scores than men, but only higher depression scores at baseline. Women with SPI reported the highest anxiety and depression scores overall.

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2020. For permissions, please email: [email protected].

Keywords: Anxiety; Depression; HADS; Implantable cardioverter-defibrillator; Indication; Sex

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