Display options
Share it on

J Clin Med. 2020 Nov 21;9(11). doi: 10.3390/jcm9113746.

Possible Correlations between Atherosclerosis, Acute Coronary Syndromes and COVID-19.

Journal of clinical medicine

Oliwia Grzegorowska, Jacek Lorkowski

Affiliations

  1. Department of Cardiology, Independent Public Regional Hospital, 71-455 Szczecin, Poland.
  2. Department of Orthopaedic and Traumatology, Central Clinical Hospital of Ministry of Interior, 02-507 Warsaw, Poland.
  3. Faculty of Health Sciences, Medical University of Mazovia, 01-793 Warsaw, Poland.

PMID: 33233333 PMCID: PMC7700642 DOI: 10.3390/jcm9113746

Abstract

An outbreak of SARS-CoV-2 infection in December 2019 became a major global concern in 2020. Since then, several articles analyzing the course, complications and mechanisms of the infection have appeared. However, there are very few papers explaining the possible correlations between COVID-19, atherosclerosis and acute coronary syndromes. We performed an analysis of PubMed, Cochrane, Google Scholar, and MEDLINE databases. As of September 15, 2020, the results were as follows: for "COVID-19" and "cardiovascular system" we obtained 687 results; for "COVID-19" and "myocardial infarction" together with "COVID-19" and "acute coronary syndrome" we obtained 328 results; for "COVID-19" and "atherosclerosis" we obtained 57 results. Some of them did not fulfill the search criteria or concerned the field of neurology. Only articles written in English, German and Polish were analyzed for a total number of 432 papers. While the link between inflammatory response, COVID- 19 and atherosclerosis still remains unclear, there is evidence that suggests a more likely correlation between them. Practitioners' efforts should be focused on the prevention of excessive inflammatory response and possible complications, while there are limited specific therapeutic options against SARS-CoV-2. Furthermore, special attention should be paid to cardioprotection during the pandemic.

Keywords: COVID-19; SARS-CoV-2; acute coronary syndrome; atherosclerosis; cardiovascular; inflammation

References

  1. Curr Atheroscler Rep. 2020 Jul 25;22(9):48 - PubMed
  2. N Engl J Med. 1999 Jan 14;340(2):115-26 - PubMed
  3. Tex Heart Inst J. 2007;34(1):11-8 - PubMed
  4. Circ Res. 2016 Apr 15;118(8):1313-26 - PubMed
  5. Cell Mol Immunol. 2016 Jan;13(1):3-10 - PubMed
  6. Br Heart J. 1975 Aug;37(8):795-803 - PubMed
  7. JAMA. 2020 Apr 7;323(13):1239-1242 - PubMed
  8. Nature. 2020 Mar;579(7798):270-273 - PubMed
  9. J Am Coll Cardiol. 2020 Aug 4;76(5):533-546 - PubMed
  10. Eur Heart J. 2005 Feb;26(4):369-75; discussion 322-4 - PubMed
  11. Thromb Haemost. 2020 Jul;120(7):1004-1024 - PubMed
  12. Circ Res. 2020 May 8;126(10):1443-1455 - PubMed
  13. Clin Cardiol. 2001 Nov;24(11):701-4 - PubMed
  14. N Engl J Med. 2020 Jun 18;382(25):2441-2448 - PubMed
  15. Clin Cardiol. 2000 Jun;23(6):453-6 - PubMed
  16. J Med Virol. 2005 Feb;75(2):185-94 - PubMed
  17. Crit Rev Oncol Hematol. 2017 Jun;114:1-12 - PubMed
  18. Chest. 2004 Nov;126(5):1417-22 - PubMed
  19. Circulation. 2020 Jun 9;141(23):1903-1914 - PubMed
  20. JAMA. 2020 Mar 17;323(11):1061-1069 - PubMed
  21. RMD Open. 2020 May;6(1): - PubMed
  22. Scand J Clin Lab Invest Suppl. 1999;230:3-11 - PubMed
  23. Eur Heart J Qual Care Clin Outcomes. 2020 Jul 1;6(3):210-216 - PubMed
  24. Medicine (Baltimore). 2009 May;88(3):154-9 - PubMed
  25. J Clin Med. 2020 Jun 02;9(6): - PubMed
  26. Semin Respir Crit Care Med. 2019 Feb;40(1):31-39 - PubMed
  27. Lancet. 2020 Mar 28;395(10229):1054-1062 - PubMed
  28. J Cell Mol Med. 2020 Jul 26;: - PubMed
  29. Acute Card Care. 2008;10(1):30-6 - PubMed
  30. Clin Infect Dis. 2020 Jul 28;71(15):762-768 - PubMed
  31. Rev Cardiovasc Med. 2020 Sep 30;21(3):315-319 - PubMed
  32. J Immunother Cancer. 2018 Jun 15;6(1):56 - PubMed
  33. J Dent Res. 2020 Sep 11;:22034520957289 - PubMed
  34. N Engl J Med. 2004 Dec 16;351(25):2611-8 - PubMed
  35. Arch Med Sci. 2020 Apr 25;16(3):490-496 - PubMed
  36. Lancet Infect Dis. 2010 Feb;10(2):83-92 - PubMed
  37. Circulation. 2003 Jan 28;107(3):391-7 - PubMed
  38. Curr Med Chem. 2011;18(21):3226-33 - PubMed
  39. Eur Heart J. 2020 May 14;41(19):1791-1794 - PubMed
  40. Lancet Infect Dis. 2009 Oct;9(10):601-10 - PubMed
  41. Viruses. 2020 May 11;12(5): - PubMed
  42. Circ Res. 2017 Oct 13;121(9):1092-1101 - PubMed
  43. Circulation. 2000 Aug 15;102(7):779-85 - PubMed
  44. Eur Heart J. 2013 Mar;34(10):719-28 - PubMed
  45. Nutrients. 2020 May 19;12(5): - PubMed
  46. Circulation. 2012 Feb 14;125(6):773-81 - PubMed
  47. Ann Intern Med. 2020 Aug 18;173(4):268-277 - PubMed
  48. Int J Cardiol. 2020 Jul 15;311:116-121 - PubMed
  49. Expert Rev Anti Infect Ther. 2019 Dec;17(12):939-942 - PubMed
  50. Semin Immunopathol. 2017 Jul;39(5):529-539 - PubMed
  51. JAMA Cardiol. 2020 Jul 1;5(7):802-810 - PubMed
  52. Atherosclerosis. 2009 Sep;206(1):251-7 - PubMed
  53. Diabetes Metab Syndr. 2020 May - Jun;14(3):247-250 - PubMed
  54. Cardiovasc Pathol. 2020 Sep - Oct;48:107233 - PubMed
  55. Ann Transl Med. 2019 Oct;7(19):504 - PubMed
  56. Sci Rep. 2017 Aug 22;7(1):9110 - PubMed
  57. JAMA. 2012 Jun 20;307(23):2526-33 - PubMed
  58. Diabetes Metab Syndr. 2020 Jul - Aug;14(4):337-339 - PubMed
  59. Microbiol Mol Biol Rev. 2012 Mar;76(1):16-32 - PubMed
  60. Blood Rev. 2016 Nov;30(6):411-420 - PubMed
  61. Angiology. 2008 Apr-May;59(2 Suppl):73S-6S - PubMed
  62. J Am Coll Cardiol. 2020 May 12;75(18):2372-2375 - PubMed
  63. SN Compr Clin Med. 2020 Aug 14;:1-6 - PubMed
  64. Medicine (Baltimore). 2020 Sep 4;99(36):e21911 - PubMed
  65. Clin Sci (Lond). 2020 Apr 17;134(7):747-750 - PubMed
  66. Lancet. 2020 Feb 15;395(10223):497-506 - PubMed
  67. Brain Behav Immun. 2020 Jul;87:59-73 - PubMed
  68. Clin Infect Dis. 2020 Jul 28;71(15):756-761 - PubMed
  69. Nat Immunol. 2005 Apr;6(4):353-60 - PubMed
  70. Int J Antimicrob Agents. 2020 May;55(5):105951 - PubMed
  71. JAMA Cardiol. 2020 Nov 1;5(11):1274-1280 - PubMed
  72. Life Sci. 2020 Jul 15;253:117723 - PubMed
  73. Int J Infect Dis. 2020 May;94:91-95 - PubMed
  74. N Engl J Med. 2020 Jun 18;382(25):2431-2440 - PubMed
  75. Circulation. 2020 May 19;141(20):1648-1655 - PubMed
  76. N Engl J Med. 2003 Oct 23;349(17):1595-604 - PubMed
  77. Vasc Health Risk Manag. 2019 Jan 17;15:1-10 - PubMed
  78. J Hypertens. 2012 Feb;30(2):375-83 - PubMed
  79. Eur Heart J Case Rep. 2020 Jul 04;4(FI1):1-6 - PubMed
  80. Lancet. 2020 Mar 28;395(10229):1033-1034 - PubMed
  81. J Clin Pharmacol. 2020 Aug;60(8):978 - PubMed
  82. J Infect. 2013 Jan;66(1):1-17 - PubMed
  83. Cell. 2020 Apr 16;181(2):271-280.e8 - PubMed
  84. Heart Lung Circ. 2013 Jun;22(6):399-411 - PubMed
  85. Cell. 2020 May 14;181(4):905-913.e7 - PubMed
  86. J Renin Angiotensin Aldosterone Syst. 2016 Dec 12;17(4): - PubMed
  87. Atherosclerosis. 2020 Feb;294:25-32 - PubMed
  88. Nat Rev Cardiol. 2020 May;17(5):259-260 - PubMed
  89. Pharmacol Res. 2018 Sep;135:230-238 - PubMed
  90. Circ Cardiovasc Qual Outcomes. 2020 Apr;13(4):e006631 - PubMed

Publication Types