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Pediatr Transplant. 2021 May;25(3):e13904. doi: 10.1111/petr.13904. Epub 2020 Nov 11.

Hospital outcomes for pediatric heart transplant recipients undergoing tracheostomy: A multi-institutional analysis.

Pediatric transplantation

Joseph A Spinner, Susan W Denfield, Kriti Puri, Shaine A Morris, John M Costello, Brady S Moffett, Yunfei Wang, Lara S Shekerdemian, Hari P Tunuguntla, Jack F Price, Jeffrey S Heinle, Iki Adachi, William J Dreyer, Antonio G Cabrera

Affiliations

  1. Department of Pediatrics, Lillie Frank Abercrombie Section of Pediatric and Congenital Cardiology, Baylor College of Medicine/Texas Children's Hospital, Houston, TX, USA.
  2. Department of Pediatrics, The Medical University of South Carolina, Charleston, SC, USA.
  3. Department of Pediatrics, Cardiovascular Research Core - Section of Cardiology, Baylor College of Medicine/Texas Children's Hospital, Houston, TX, USA.
  4. Division of Critical Care Medicine, Department of Pediatrics, Baylor College of Medicine/Texas Children's Hospital, Houston, TX, USA.
  5. Division of Congenital Heart Surgery, Department of Surgery, Baylor College of Medicine/Texas Children's Hospital, Houston, TX, USA.
  6. Division of Pediatric Cardiology, Department of Pediatrics/Primary Children's Hospital Heart Center, University of Utah, Salt Lake City, UT, USA.

PMID: 33179431 DOI: 10.1111/petr.13904

Abstract

Tracheostomy is associated with increased mortality and resource utilization in children with CHD. However, the prevalence and hospital outcomes of tracheostomy in children with HTx are not known. We describe the prevalence and compare the post-HTx hospital outcomes of pediatric patients with Pre-TT and Post-TT to those without tracheostomy. A multi-institutional retrospective cohort study was performed using the Pediatric Health Information System database. Hospital mortality, mediastinitis, LOS, and costs were compared among patients with Pre-TT, Post-TT, and no tracheostomy. Pre-TT was identified in 29 (1.1%) and Post-TT was identified in 41 (1.6%) of 2603 index HTx hospitalizations. Patients with Pre-TT were younger and more likely to have CHD, a non-cardiac birth defect, or an airway anomaly compared to those without Pre-TT. Pre-TT was not independently associated with increased post-HTx in-hospital mortality. Age at HTx < 1 year, CHD, and Post-TT were associated with increased in-hospital mortality. Pre-TT that occurred during the HTx hospitalization and Post-TT were associated with increased resource utilization. Tracheostomy was not associated with mediastinitis.

© 2020 Wiley Periodicals LLC.

Keywords: outcome; pediatric heart transplant; tracheostomy

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