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Sci Rep. 2020 Dec 03;10(1):21040. doi: 10.1038/s41598-020-77709-4.

Time dynamics of COVID-19.

Scientific reports

Cody Carroll, Satarupa Bhattacharjee, Yaqing Chen, Paromita Dubey, Jianing Fan, Álvaro Gajardo, Xiner Zhou, Hans-Georg Müller, Jane-Ling Wang

Affiliations

  1. Department of Statistics, University of California, Davis, Davis, CA, 95616, USA.
  2. Department of Statistics, Stanford University, Stanford, CA, 94305, USA.
  3. Department of Statistics, University of California, Davis, Davis, CA, 95616, USA. [email protected].

PMID: 33273598 PMCID: PMC7712909 DOI: 10.1038/s41598-020-77709-4

Abstract

We apply tools from functional data analysis to model cumulative trajectories of COVID-19 cases across countries, establishing a framework for quantifying and comparing cases and deaths across countries longitudinally. It emerges that a country's trajectory during an initial first month "priming period" largely determines how the situation unfolds subsequently. We also propose a method for forecasting case counts, which takes advantage of the common, latent information in the entire sample of curves, instead of just the history of a single country. Our framework facilitates to quantify the effects of demographic covariates and social mobility on doubling rates and case fatality rates through a time-varying regression model. Decreased workplace mobility is associated with lower doubling rates with a roughly 2 week delay, and case fatality rates exhibit a positive feedback pattern.

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