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Adamo A, Delfino P, Gatti A, et al. HS-5 and HS-27A Stromal Cell Lines to Study Bone Marrow Mesenchymal Stromal Cell-Mediated Support to Cancer Development. Front Cell Dev Biol. 2020;8:584232doi: 10.3389/fcell.2020.584232.
Adamo, A., Delfino, P., Gatti, A., Bonato, A., Takam Kamga, P., Bazzoni, R., Ugel, S., Mercuri, A., Caligola, S., & Krampera, M. (2020). HS-5 and HS-27A Stromal Cell Lines to Study Bone Marrow Mesenchymal Stromal Cell-Mediated Support to Cancer Development. Frontiers in cell and developmental biology, 8584232. https://doi.org/10.3389/fcell.2020.584232
Adamo, Annalisa, et al. "HS-5 and HS-27A Stromal Cell Lines to Study Bone Marrow Mesenchymal Stromal Cell-Mediated Support to Cancer Development." Frontiers in cell and developmental biology vol. 8 (2020): 584232. doi: https://doi.org/10.3389/fcell.2020.584232
Adamo A, Delfino P, Gatti A, Bonato A, Takam Kamga P, Bazzoni R, Ugel S, Mercuri A, Caligola S, Krampera M. HS-5 and HS-27A Stromal Cell Lines to Study Bone Marrow Mesenchymal Stromal Cell-Mediated Support to Cancer Development. Front Cell Dev Biol. 2020 Nov 05;8:584232. doi: 10.3389/fcell.2020.584232. eCollection 2020. PMID: 33251214; PMCID: PMC7674674.
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Front Cell Dev Biol. 2020 Nov 05;8:584232. doi: 10.3389/fcell.2020.584232. eCollection 2020.

HS-5 and HS-27A Stromal Cell Lines to Study Bone Marrow Mesenchymal Stromal Cell-Mediated Support to Cancer Development.

Frontiers in cell and developmental biology

Annalisa Adamo, Pietro Delfino, Alessandro Gatti, Alice Bonato, Paul Takam Kamga, Riccardo Bazzoni, Stefano Ugel, Angela Mercuri, Simone Caligola, Mauro Krampera

Affiliations

  1. Stem Cell Research Laboratory, Section of Hematology, Department of Medicine, University of Verona, Verona, Italy.
  2. Department of Medicine, Section of Immunology, University of Verona, Verona, Italy.
  3. Department of Diagnostic and Public Health, University of Verona, Verona, Italy.
  4. EA4340-BCOH, Biomarker in Cancerology and Onco-Haematology, UVSQ, Université Paris Saclay, Boulogne-Billancourt, France.

PMID: 33251214 PMCID: PMC7674674 DOI: 10.3389/fcell.2020.584232

Abstract

In this study, we compared the overall gene and pathway expression profiles of HS-5 and HS-27A stromal cell lines with those of primary bone marrow MSCs to verify if they can be considered a reliable alternative tool for evaluating the contribution of MSCs in tumor development and immunomodulation. Indeed, due to their easier manipulation

Copyright © 2020 Adamo, Delfino, Gatti, Bonato, Takam Kamga, Bazzoni, Ugel, Mercuri, Caligola and Krampera.

Keywords: immunomodulation; mesenchymal stromal cells; stromal cell lines; tumor biology; tumor escape

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