Am J Hypertens. 2021 May 22;34(5):494-503. doi: 10.1093/ajh/hpaa189.
Twenty-Five-Year Changes in Office and Ambulatory Blood Pressure: Results From the Coronary Artery Risk Development in Young Adults (CARDIA) Study.
American journal of hypertension
Joshua D Bundy, Byron C Jaeger, Mark D Huffman, Sarah S Knox, S Justin Thomas, Daichi Shimbo, John N Booth, Cora E Lewis, Lloyd J Edwards, Joseph E Schwartz, Paul Muntner
Affiliations
Affiliations
- Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA.
- Tulane University Translational Science Institute, New Orleans, Louisiana, USA.
- Department of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama, USA.
- Department of Preventive Medicine and Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
- Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
- The George Institute for Global Health, University of New South Wales, Sydney, Australia.
- Department of Epidemiology, West Virginia University School of Public Health, Morgantown, West Virginia, USA.
- Department of Psychiatry, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA.
- Department of Medicine, Columbia University Medical Center, New York, New York, USA.
- Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
- CTI Clinical Trials and Consulting Services, Inc., Covington, Kentucky, USA.
- Department of Psychiatry, Stony Brook University, New York, New York, USA.
PMID: 33201230
PMCID: PMC8140654 DOI: 10.1093/ajh/hpaa189
Abstract
BACKGROUND: Blood pressure (BP) measured in the office setting increases from early through later adulthood. However, it is unknown to what extent out-of-office BP derived via ambulatory BP monitoring (ABPM) increases over time, and which participant characteristics and risk factors might contribute to these increases.
METHODS: We assessed 25-year change in office- and ABPM-derived BP across sex, race, diabetes mellitus (DM), and body mass index (BMI) subgroups in the Coronary Artery Risk Development in Young Adults study using multivariable-adjusted linear mixed effects models.
RESULTS: We included 288 participants who underwent ABPM at the Year 5 Exam (mean [SD] age, 25.1 [3.7]; 45.8% men) and 455 participants who underwent ABPM at the Year 30 Exam (mean [SD] age, 49.5 [3.7]; 42.0% men). Office, daytime, and nighttime systolic BP (SBP) increased 12.8 (95% confidence interval [CI], 7.6-17.9), 14.7 (95% CI, 9.7-19.8), and 16.6 (95% CI, 11.4-21.8) mm Hg, respectively, over 25 years. Office SBP increased 6.5 (95% CI, 2.3-10.6) mm Hg more among black compared with white participants. Daytime SBP increased 6.3 (95% CI, 0.2-12.4) mm Hg more among participants with a BMI ≥25 vs. <25 kg/m2. Nighttime SBP increased 4.7 (95% CI, 0.5-8.9) mm Hg more among black compared with white participants, and 17.3 (95% CI, 7.2-27.4) mm Hg more among participants with vs. without DM.
CONCLUSIONS: Office- and ABPM-derived BP increased more from early through middle adulthood among black adults and participants with DM and BMI ≥25 kg/m2.
© American Journal of Hypertension, Ltd 2020. All rights reserved. For Permissions, please email: [email protected].
Keywords: aging; ambulatory blood pressure monitoring; blood pressure; epidemiology; health status disparities; hypertension; risk factors
References
- Hypertension. 2011 Jan;57(1):3-10 - PubMed
- PLoS Med. 2011 Jun;8(6):e1000440 - PubMed
- Hypertension. 2012 Dec;60(6):1393-9 - PubMed
- J Clin Hypertens (Greenwich). 2019 Feb;21(2):184-192 - PubMed
- Am J Hypertens. 2017 Oct 1;30(10):961-967 - PubMed
- J Am Heart Assoc. 2018 Jul 11;7(14): - PubMed
- Am J Physiol Regul Integr Comp Physiol. 2004 May;286(5):R803-13 - PubMed
- Circulation. 2019 Mar 5;139(10):e56-e528 - PubMed
- Hypertension. 2020 Sep;76(3):759-765 - PubMed
- Circulation. 2006 Dec 19;114(25):2780-7 - PubMed
- Hypertension. 2003 Feb;41(2):207-10 - PubMed
- J Cardiopulm Rehabil. 1989 Nov;9(11):448-459 - PubMed
- Stat Med. 2005 Oct 15;24(19):2911-35 - PubMed
- JAMA. 2017 Jan 10;317(2):165-182 - PubMed
- Am J Hypertens. 1995 Oct;8(10 Pt 1):978-86 - PubMed
- Am J Hypertens. 2018 Nov 13;31(12):1247-1254 - PubMed
- Hypertension. 2004 Jun;43(6):1239-45 - PubMed
- Am J Hypertens. 2015 May;28(5):640-8 - PubMed
- JAMA Cardiol. 2020 Mar 1;5(3):19-26 - PubMed
- Prev Med. 1987 Mar;16(2):235-51 - PubMed
- Hypertension. 2002 Dec;40(6):914-9 - PubMed
- Am Heart J. 2005 Jul;150(1):153-60 - PubMed
- Obstet Gynecol. 2008 Dec;112(6):1294-1302 - PubMed
- J Am Soc Hypertens. 2017 Apr;11(4):204-212.e5 - PubMed
- J Hypertens. 2014 Dec;32(12):2332-40; discussion 2340 - PubMed
- Diabetes Care. 2017 Sep;40(9):1273-1284 - PubMed
- Hypertension. 2008 Apr;51(4):952-9 - PubMed
- Curr Hypertens Rep. 2019 May 22;21(7):51 - PubMed
- JAMA. 2018 Apr 10;319(14):1444-1472 - PubMed
- J Hypertens. 2018 Apr;36(4):720-733 - PubMed
- N Engl J Med. 2011 Nov 17;365(20):1876-85 - PubMed
- Blood Press Monit. 2007 Aug;12(4):255-62 - PubMed
- N Engl J Med. 2006 Jun 1;354(22):2368-74 - PubMed
- JAMA. 2019 Aug 6;322(5):409-420 - PubMed
- Hypertension. 1999 May;33(5):1195-200 - PubMed
- Circulation. 2016 Aug 9;134(6):441-50 - PubMed
- JAMA Cardiol. 2019 Sep 1;4(9):910-917 - PubMed
- J Clin Epidemiol. 1988;41(11):1105-16 - PubMed
- Hypertension. 2018 Jun;71(6):997-1009 - PubMed
- J Hypertens. 2013 Sep;31(9):1731-68 - PubMed
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