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Jiang MC, Hu CC, Hsu WL, et al. Fusion of a Novel Native Signal Peptide Enhanced the Secretion and Solubility of Bioactive Human Interferon Gamma Glycoproteins in . Front Plant Sci. 2020;11:594758doi: 10.3389/fpls.2020.594758.
Jiang, M. C., Hu, C. C., Hsu, W. L., Hsu, T. L., Lin, N. S., & Hsu, Y. H. (2020). Fusion of a Novel Native Signal Peptide Enhanced the Secretion and Solubility of Bioactive Human Interferon Gamma Glycoproteins in . Frontiers in plant science, 11594758. https://doi.org/10.3389/fpls.2020.594758
Jiang, Min-Chao, et al. "Fusion of a Novel Native Signal Peptide Enhanced the Secretion and Solubility of Bioactive Human Interferon Gamma Glycoproteins in ." Frontiers in plant science vol. 11 (2020): 594758. doi: https://doi.org/10.3389/fpls.2020.594758
Jiang MC, Hu CC, Hsu WL, Hsu TL, Lin NS, Hsu YH. Fusion of a Novel Native Signal Peptide Enhanced the Secretion and Solubility of Bioactive Human Interferon Gamma Glycoproteins in . Front Plant Sci. 2020 Nov 12;11:594758. doi: 10.3389/fpls.2020.594758. eCollection 2020. PMID: 33281853; PMCID: PMC7688984.
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Front Plant Sci. 2020 Nov 12;11:594758. doi: 10.3389/fpls.2020.594758. eCollection 2020.

Fusion of a Novel Native Signal Peptide Enhanced the Secretion and Solubility of Bioactive Human Interferon Gamma Glycoproteins in .

Frontiers in plant science

Min-Chao Jiang, Chung-Chi Hu, Wei-Li Hsu, Tsui-Ling Hsu, Na-Sheng Lin, Yau-Heiu Hsu

Affiliations

  1. Ph.D. Program in Microbial Genomics, National Chung Hsing University and Academia Sinica, Taichung, Taiwan.
  2. Graduate Institute of Biotechnology, National Chung Hsing University, Taichung, Taiwan.
  3. Advanced Plant Biotechnology Center, National Chung Hsing University, Taichung, Taiwan.
  4. Graduate Institute of Microbiology and Public Health, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
  5. Genomics Research Center, Academia Sinica, Taipei, Taiwan.
  6. Institute of Plant and Microbial Biology, Academia Sinica, Taipei, Taiwan.

PMID: 33281853 PMCID: PMC7688984 DOI: 10.3389/fpls.2020.594758

Abstract

Plant viruses may serve as expression vectors for the efficient production of pharmaceutical proteins in plants. However, the downstream processing and post-translational modifications of the target proteins remain the major challenges. We have previously developed an expression system derived from

Copyright © 2020 Jiang, Hu, Hsu, Hsu, Lin and Hsu.

Keywords: Bamboo mosaic virus; anti-virus activity; glycosylation; interferon gamma; plant viral vector; signal peptides

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