Display options
Cite
Omori T, Nakamori S, Ohta-Ogo K, et al. Autopsy study of pulmonary capillary hemangiomatosis with inflammatory cell infiltration into the myocardium. Pulm Circ. 2020;10(4):2045894020960600doi: 10.1177/2045894020960600.
Omori, T., Nakamori, S., Ohta-Ogo, K., Matsuda, A., Ogihara, Y., Yamada, N., Imanaka-Yoshida, K., Ito, M., & Dohi, K. (2020). Autopsy study of pulmonary capillary hemangiomatosis with inflammatory cell infiltration into the myocardium. Pulmonary circulation, 10(4), 2045894020960600. https://doi.org/10.1177/2045894020960600
Omori, Taku, et al. "Autopsy study of pulmonary capillary hemangiomatosis with inflammatory cell infiltration into the myocardium." Pulmonary circulation vol. 10,4 (2020): 2045894020960600. doi: https://doi.org/10.1177/2045894020960600
Omori T, Nakamori S, Ohta-Ogo K, Matsuda A, Ogihara Y, Yamada N, Imanaka-Yoshida K, Ito M, Dohi K. Autopsy study of pulmonary capillary hemangiomatosis with inflammatory cell infiltration into the myocardium. Pulm Circ. 2020 Nov 23;10(4):2045894020960600. doi: 10.1177/2045894020960600. eCollection 2020. PMID: 33282187; PMCID: PMC7686619.
Copy Download .nbib Format: NLM
Share it on

Pulm Circ. 2020 Nov 23;10(4):2045894020960600. doi: 10.1177/2045894020960600. eCollection 2020.

Autopsy study of pulmonary capillary hemangiomatosis with inflammatory cell infiltration into the myocardium.

Pulmonary circulation

Taku Omori, Shiro Nakamori, Keiko Ohta-Ogo, Akimasa Matsuda, Yoshito Ogihara, Norikazu Yamada, Kyoko Imanaka-Yoshida, Masaaki Ito, Kaoru Dohi

Affiliations

  1. Department of Cardiology and Nephrology, Mie University Hospital, Tsu, Japan.
  2. Department of Pathology, National Cerebral and Cardiovascular Center, Suita, Japan.
  3. Hakusan Clinic, Tsu, Japan.
  4. Department of Cardiology, Kuwana City Medical Center, Kuwana, Japan.
  5. Department of Pathology and Matrix Biology, Mie University Graduate School of Medicine, Tsu, Japan.
  6. Mie University Research Center for Matrix Biology, Tsu, Japan.

PMID: 33282187 PMCID: PMC7686619 DOI: 10.1177/2045894020960600

Abstract

Pulmonary capillary hemangiomatosis is a rare form of pulmonary artery hypertension; to date, only few descriptions of myocardial pathology in pulmonary capillary hemangiomatosis have been reported in the literature. We report the case of a Japanese female patient who was diagnosed with pulmonary capillary hemangiomatosis combined with acute myocardial inflammation on performing autopsy. She was admitted to our hospital because of acute pneumonia and subsequently suddenly developed severe hypoxemia with breathing difficulty and died 13 days after admission. At autopsy, the histology of the lung was consistent with pulmonary capillary hemangiomatosis. Additionally, a diffuse severe infiltration of inflammatory cells was associated with edema in the myocardium. Myocytolysis was limited and fibrosis was absent. To the best of our knowledge, pulmonary capillary hemangiomatosis with acute myocarditis-like histological findings has been described for the first time through our case.

© The Author(s) 2020.

Keywords: myocardium; pathology; pulmonary artery hypertension; pulmonary capillary hemangiomatosis

Conflict of interest statement

Conflict of interest: The author(s) declare that there is no conflict of interest.

References

  1. Thorax. 1971 Jul;26(4):429-34 - PubMed
  2. JAMA. 1981 Aug 7;246(6):667-71 - PubMed
  3. Arch Pathol Lab Med. 2015 Feb;139(2):274-7 - PubMed
  4. Histopathology. 1978 Nov;2(6):401-6 - PubMed
  5. Hum Pathol. 1987 Jun;18(6):619-24 - PubMed
  6. Radiographics. 2007 May-Jun;27(3):867-82 - PubMed
  7. Heart. 2008 Apr;94(4):450-6 - PubMed
  8. J Thorac Imaging. 2010 Aug;25(3):W89-92 - PubMed
  9. Circulation. 2006 Jan 31;113(4):593-5 - PubMed

Publication Types