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Verlinden W, Van Mieghem E, Depauw L, et al. Non-Alcoholic Steatohepatitis Decreases Microsomal Liver Function in the Absence of Fibrosis. Biomedicines. 2020;8(12)doi: 10.3390/biomedicines8120546.
Verlinden, W., Van Mieghem, E., Depauw, L., Vanwolleghem, T., Vonghia, L., Weyler, J., Driessen, A., Callens, D., Roosens, L., Dirinck, E., Verrijken, A., Gaal, L. V., & Francque, S. (2020). Non-Alcoholic Steatohepatitis Decreases Microsomal Liver Function in the Absence of Fibrosis. Biomedicines, 8(12), . https://doi.org/10.3390/biomedicines8120546
Verlinden, Wim, et al. "Non-Alcoholic Steatohepatitis Decreases Microsomal Liver Function in the Absence of Fibrosis." Biomedicines vol. 8,12 (2020). doi: https://doi.org/10.3390/biomedicines8120546
Verlinden W, Van Mieghem E, Depauw L, Vanwolleghem T, Vonghia L, Weyler J, Driessen A, Callens D, Roosens L, Dirinck E, Verrijken A, Gaal LV, Francque S. Non-Alcoholic Steatohepatitis Decreases Microsomal Liver Function in the Absence of Fibrosis. Biomedicines. 2020 Nov 27;8(12). doi: 10.3390/biomedicines8120546. PMID: 33261113; PMCID: PMC7760673.
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Biomedicines. 2020 Nov 27;8(12). doi: 10.3390/biomedicines8120546.

Non-Alcoholic Steatohepatitis Decreases Microsomal Liver Function in the Absence of Fibrosis.

Biomedicines

Wim Verlinden, Eugénie Van Mieghem, Laura Depauw, Thomas Vanwolleghem, Luisa Vonghia, Jonas Weyler, Ann Driessen, Dirk Callens, Laurence Roosens, Eveline Dirinck, An Verrijken, Luc Van Gaal, Sven Francque

Affiliations

  1. Laboratory of Experimental Medicine and Pediatrics, Division of Gastroenterology and Hepatology, University of Antwerp, 2610 Antwerp, Belgium.
  2. Department of Gastroenterology and Hepatology, Antwerp University Hospital, 2650 Antwerp, Belgium.
  3. Department of Pathology, Antwerp University Hospital, 2650 Antwerp, Belgium.
  4. Department of Clinical Biology, Antwerp University Hospital, 2650 Antwerp, Belgium.
  5. Department of Endocrinology, Diabetology and Metabolism, Antwerp University Hospital, 2650 Antwerp, Belgium.

PMID: 33261113 PMCID: PMC7760673 DOI: 10.3390/biomedicines8120546

Abstract

The incidence of non-alcoholic fatty liver disease (NAFLD) is rising across the globe, with the presence of steatohepatitis leading to a more aggressive clinical course. Currently, the diagnosis of non-alcoholic steatohepatitis (NASH) is based on histology, though with the high prevalence of NAFLD, a non-invasive method is needed. The

Keywords: NASH; aminopyrine; breath test; liver function; microsomal; steatohepatitis

References

  1. J Hepatol. 2010 Aug;53(2):372-84 - PubMed
  2. J Thorac Oncol. 2010 Sep;5(9):1315-6 - PubMed
  3. Xenobiotica. 1999 Feb;29(2):187-93 - PubMed
  4. J Gastrointestin Liver Dis. 2013 Jun;22(2):149-56 - PubMed
  5. Lab Invest. 2018 Oct;98(10):1263-1275 - PubMed
  6. Liver Int. 2012 Sep;32(8):1242-52 - PubMed
  7. Am J Gastroenterol. 2003 Oct;98(10):2335-6 - PubMed
  8. Isotopes Environ Health Stud. 2002 Jun;38(2):71-7 - PubMed
  9. J Clin Gastroenterol. 2014 Jan;48(1):59-65 - PubMed
  10. Physiol Behav. 2017 Jul 1;176:139-148 - PubMed
  11. Nat Rev Gastroenterol Hepatol. 2018 Aug;15(8):461-478 - PubMed
  12. JAMA Netw Open. 2019 Oct 2;2(10):e1912565 - PubMed
  13. Xenobiotica. 2018 Jun;48(6):576-583 - PubMed
  14. J Hepatol. 2008 May;48(5):829-34 - PubMed
  15. Obes Surg. 2007 Jan;17(1):45-56 - PubMed
  16. Drug Metab Rev. 2017 May;49(2):197-211 - PubMed
  17. Hepatology. 2005 Jun;41(6):1313-21 - PubMed
  18. Hepatology. 2017 May;65(5):1557-1565 - PubMed
  19. Hepatology. 2008 Sep;48(3):792-8 - PubMed
  20. Asian Pac J Cancer Prev. 2018 Aug 24;19(8):2057-2070 - PubMed
  21. Br J Clin Pharmacol. 2011 Nov;72(5):836-8 - PubMed
  22. J Hepatol. 2000 Dec;33(6):893-901 - PubMed
  23. Liver. 2001 Aug;21(4):260-5 - PubMed
  24. Acta Gastroenterol Belg. 2018 Jan-Mar;81(1):55-81 - PubMed
  25. J Gastroenterol Hepatol. 2011 Sep;26(9):1411-6 - PubMed
  26. J Gastroenterol Hepatol. 2003 Apr;18(4):445-9 - PubMed
  27. J Pharm Pharm Sci. 2016 Oct - Dec;19(4):423-429 - PubMed
  28. Hepatology. 2013 Oct;58(4):1497-507 - PubMed
  29. Eur J Gastroenterol Hepatol. 2010 Dec;22(12):1449-57 - PubMed
  30. Gut. 1992 Jun;33(6):836-42 - PubMed
  31. Hepatology. 2011 Mar;53(3):810-20 - PubMed
  32. Clin Pharmacol Ther. 1976 Oct;20(4):484-92 - PubMed
  33. Hepatology. 2018 Jan;67(1):328-357 - PubMed
  34. World J Hepatol. 2015 Jun 18;7(11):1450-9 - PubMed
  35. Aliment Pharmacol Ther. 2002 Apr;16(4):717-25 - PubMed
  36. Hepatology. 1982 May-Jun;2(3):317-22 - PubMed
  37. Dig Dis Sci. 2013 Jan;58(1):33-41 - PubMed
  38. Yale J Biol Med. 1977 Sep-Oct;50(5):437-55 - PubMed
  39. Hepatology. 2014 Aug;60(2):565-75 - PubMed
  40. Med Hypotheses. 2019 Jan;122:188-197 - PubMed
  41. J Hepatol. 2015 Jul;63(1):164-73 - PubMed
  42. Br J Clin Pharmacol. 1980 Oct;10 Suppl 2:299S-308S - PubMed
  43. Aliment Pharmacol Ther. 2002 Dec;16(12):1977-96 - PubMed
  44. Gastroenterology. 2001 Jul;121(1):91-100 - PubMed
  45. Clin Sci (Lond). 2006 Aug;111(2):135-43 - PubMed
  46. J Hepatol. 2020 May;72(5):828-838 - PubMed
  47. Lab Invest. 2012 Oct;92(10):1428-39 - PubMed
  48. Eur J Med Res. 2011 Jun 21;16(6):258-64 - PubMed
  49. Clin Gastroenterol Hepatol. 2005 Mar;3(3):279-85 - PubMed
  50. Biometrics. 1988 Sep;44(3):837-45 - PubMed
  51. Clin Pharmacokinet. 1994 Sep;27(3):216-48 - PubMed
  52. J Clin Gastroenterol. 2008 Apr;42(4):408-12 - PubMed
  53. J Clin Gastroenterol. 2011 Jan;45(1):59-63 - PubMed
  54. Br Med J (Clin Res Ed). 1986 Jan 4;292(6512):13-5 - PubMed

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