Display options
Cite
Fridley JS, Syed S, Niu T, et al. Presentation of spinal cord and column tumors. Neurooncol Pract. 2020;7:i18-i24doi: 10.1093/nop/npaa051.
Fridley, J. S., Syed, S., Niu, T., Leary, O. P., & Gokaslan, Z. L. (2020). Presentation of spinal cord and column tumors. Neuro-oncology practice, 7i18-i24. https://doi.org/10.1093/nop/npaa051
Fridley, Jared S, et al. "Presentation of spinal cord and column tumors." Neuro-oncology practice vol. 7 (2020): i18-i24. doi: https://doi.org/10.1093/nop/npaa051
Fridley JS, Syed S, Niu T, Leary OP, Gokaslan ZL. Presentation of spinal cord and column tumors. Neurooncol Pract. 2020 Nov 18;7:i18-i24. doi: 10.1093/nop/npaa051. eCollection 2020 Nov. PMID: 33299570; PMCID: PMC7705528.
Copy Download .nbib Format: NLM
Share it on

Neurooncol Pract. 2020 Nov 18;7:i18-i24. doi: 10.1093/nop/npaa051. eCollection 2020 Nov.

Presentation of spinal cord and column tumors.

Neuro-oncology practice

Jared S Fridley, Sohail Syed, Tianyi Niu, Owen P Leary, Ziya L Gokaslan

Affiliations

  1. Department of Neurosurgery, Warren Alpert School of Medicine of Brown University, Providence, Rhode Island, USA.

PMID: 33299570 PMCID: PMC7705528 DOI: 10.1093/nop/npaa051

Abstract

Metastatic spine disease occurs in more than 10% of all cancer patients. Advances in systemic treatment for cancer has led to improved overall survival for many types of cancer, which has increased the overall incidence of spinal metastases. The most common presenting complaint of patients with spinal metastases is pain. Pain originating from spinal metastases can be oncological, mechanical, and/or neurological in nature. Early recognition of these symptoms is helpful to guide treatment and accurately gauge patient prognosis. Unfortunately, the prevalence of degenerative back pain in the general population can complicate early clinical recognition of patients with metastatic spine disease. Therefore, back pain in any patient with a history of malignancy should prompt clinicians to perform an expedited workup for metastatic disease of the spine. Diagnostic imaging and laboratory studies are part of the initial work up. Obtaining pathology via biopsy to establish tumor histology is essential to determine the appropriate treatment.

© The Author(s) 2020. Published by Oxford University Press on behalf of the Society for Neuro-Oncology and the European Association of Neuro-Oncology. All rights reserved. For permissions, please e-mail: [email protected].

Keywords: NOMS; cancer; epidural cord compression; spine metastases; spine tumor

References

  1. Neurosurg Rev. 2001 Mar;24(1):1-5; discussion 6-7 - PubMed
  2. Spine (Phila Pa 1976). 2012 Apr 1;37(7):573-82 - PubMed
  3. Spine (Phila Pa 1976). 1987 Nov;12(9):843-51 - PubMed
  4. Eur J Radiol. 2012 May;81(5):1007-15 - PubMed
  5. Acta Neurochir (Wien). 2012 May;154(5):871-7; discussion 877 - PubMed
  6. Acta Orthop Scand. 1995 Apr;66(2):143-6 - PubMed
  7. Eur J Cancer Care (Engl). 2010 Nov;19(6):755-60 - PubMed
  8. Oncol Lett. 2020 Apr;19(4):3137-3144 - PubMed
  9. Cancer. 1997 Oct 15;80(8 Suppl):1614-27 - PubMed
  10. Neurosurgery. 1979 Dec;5(6):726-46 - PubMed
  11. Eur Spine J. 2008 Nov;17(11):1488-95 - PubMed
  12. J Neurooncol. 2015 Jun;123(2):267-75 - PubMed
  13. Cancer. 2005 Jan 15;103(2):320-8 - PubMed
  14. Spine (Phila Pa 1976). 2001 Feb 1;26(3):298-306 - PubMed
  15. BMJ. 2008 Nov 27;337:a2538 - PubMed
  16. J Orthop Surg Res. 2008 Aug 28;3:37 - PubMed
  17. Int Orthop. 1995;19(5):309-11 - PubMed
  18. Spine (Phila Pa 1976). 1990 Nov;15(11):1110-3 - PubMed
  19. Eur Spine J. 2015 Oct;24(10):2142-9 - PubMed
  20. Skeletal Radiol. 2014 Nov;43(11):1503-13 - PubMed
  21. QJM. 2014 Apr;107(4):277-82 - PubMed
  22. Clin Orthop Relat Res. 1997 Feb;(335):54-63 - PubMed
  23. Spine J. 2019 Sep;19(9):1540-1547 - PubMed
  24. Am J Med. 1981 Jun;70(6):1181-8 - PubMed
  25. J Neurosurg. 1983 Jul;59(1):111-8 - PubMed
  26. J Neurosurg Spine. 2018 Jan;28(1):79-87 - PubMed
  27. Spine (Phila Pa 1976). 2005 Oct 1;30(19):2186-91 - PubMed
  28. Clin Oncol (R Coll Radiol). 2002 Dec;14(6):472-80 - PubMed
  29. CA Cancer J Clin. 2016 Jan-Feb;66(1):7-30 - PubMed
  30. J Surg Oncol. 1983 Jul;23(3):175-80 - PubMed
  31. J Clin Oncol. 2011 Aug 1;29(22):3072-7 - PubMed
  32. Eur Radiol. 2011 Dec;21(12):2604-17 - PubMed
  33. Eur Spine J. 2013 Mar;22 Suppl 1:S21-6 - PubMed
  34. J Neuroradiol. 2007 Dec;34(5):311-21 - PubMed
  35. Oncologist. 2013 Jun;18(6):744-51 - PubMed

Publication Types