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Rodríguez-Núñez I, Pontes RB, Romero F, et al. Effects of physical exercise on baroreflex sensitivity and renal sympathetic nerve activity in chronic nicotine-treated rats. Can J Physiol Pharmacol. 2020;99(8):786-794doi: 10.1139/cjpp-2020-0381.
Rodríguez-Núñez, I., Pontes, R. B., Romero, F., & Campos, R. R. (2021). Effects of physical exercise on baroreflex sensitivity and renal sympathetic nerve activity in chronic nicotine-treated rats. Canadian journal of physiology and pharmacology, 99(8), 786-794. https://doi.org/10.1139/cjpp-2020-0381
Rodríguez-Núñez, Iván, et al. "Effects of physical exercise on baroreflex sensitivity and renal sympathetic nerve activity in chronic nicotine-treated rats." Canadian journal of physiology and pharmacology vol. 99,8 (2021): 786-794. doi: https://doi.org/10.1139/cjpp-2020-0381
Rodríguez-Núñez I, Pontes RB, Romero F, Campos RR. Effects of physical exercise on baroreflex sensitivity and renal sympathetic nerve activity in chronic nicotine-treated rats. Can J Physiol Pharmacol. 2021 Aug;99(8):786-794. doi: 10.1139/cjpp-2020-0381. Epub 2020 Dec 08. PMID: 33290163.
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Can J Physiol Pharmacol. 2021 Aug;99(8):786-794. doi: 10.1139/cjpp-2020-0381. Epub 2020 Dec 08.

Effects of physical exercise on baroreflex sensitivity and renal sympathetic nerve activity in chronic nicotine-treated rats.

Canadian journal of physiology and pharmacology

Iván Rodríguez-Núñez, Roberto B Pontes, Fernando Romero, Ruy R Campos

Affiliations

  1. Departamento de Fisiologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil.
  2. Departamento de Kinesiología, Facultad de Medicina, Universidad de Concepción, Chile.
  3. Programa de Doctorado en Ciencias Médicas, Departamento de Cirugía, Facultad de Medicina, Universidad de La Frontera, Temuco. Chile.

PMID: 33290163 DOI: 10.1139/cjpp-2020-0381

Abstract

Chronic nicotine exposure may increase cardiovascular risk by impairing the cardiac autonomic function. Besides, physical exercise (PE) has shown to improve cardiovascular health. Thus, we aimed to investigate the effects of PE on baroreflex sensitivity (BRS), heart rate variability (HRV), and sympathetic nerve activity (SNA) in chronically nicotine-exposed rats. Male Wistar rats were assigned to four independent groups: Control (treated with saline solution), Control+Ex (treated with saline and submitted to treadmill training), Nicotine (treated with Nicotine), and Nicotine+Ex (treated with nicotine and submitted to treadmill training). Nicotine (1 mg·kg

Keywords: activité nerveuse sympathique rénale; arterial baroreceptor; barorécepteur artériel; exercice physique; heart rate variability; nicotine; physical exercise; renal sympathetic nerve activity; variabilité de la fréquence cardiaque

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