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Okawara S, Bando K, Tsukada J. Light chain-positive rod-like inclusions in bone marrow plasma cells associated with monoclonal gammopathy of renal significance. Clin Case Rep. 2020;8(12):3621-3622doi: 10.1002/ccr3.3362.
Okawara, S., Bando, K., & Tsukada, J. (2020). Light chain-positive rod-like inclusions in bone marrow plasma cells associated with monoclonal gammopathy of renal significance. Clinical case reports, 8(12), 3621-3622. https://doi.org/10.1002/ccr3.3362
Okawara, Sayoko, et al. "Light chain-positive rod-like inclusions in bone marrow plasma cells associated with monoclonal gammopathy of renal significance." Clinical case reports vol. 8,12 (2020): 3621-3622. doi: https://doi.org/10.1002/ccr3.3362
Okawara S, Bando K, Tsukada J. Light chain-positive rod-like inclusions in bone marrow plasma cells associated with monoclonal gammopathy of renal significance. Clin Case Rep. 2020 Sep 21;8(12):3621-3622. doi: 10.1002/ccr3.3362. eCollection 2020 Dec. PMID: 33364007; PMCID: PMC7752359.
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Clin Case Rep. 2020 Sep 21;8(12):3621-3622. doi: 10.1002/ccr3.3362. eCollection 2020 Dec.

Light chain-positive rod-like inclusions in bone marrow plasma cells associated with monoclonal gammopathy of renal significance.

Clinical case reports

Sayoko Okawara, Kenichiro Bando, Junichi Tsukada

Affiliations

  1. Hematology University of Occupational and Environmental Health Kitakyushu Japan.
  2. The Second Department of Internal Medicine University of Occupational and Environmental Health Kitakyushu Japan.

PMID: 33364007 PMCID: PMC7752359 DOI: 10.1002/ccr3.3362

Abstract

Rod-like inclusions have rarely been described in cases of monoclonal gammopathy of renal significance or multiple myeloma. The key finding in our case is the strong κ-light chain positivity of rod-like inclusions in plasma cells, which confirms their immunoglobulin nature. Therapeutic benefit of bortezomib was also observed.

© 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.

Keywords: monoclonal gammopathy of renal significance; rod‐like inclusion and plasma cell

Conflict of interest statement

The authors have no conflicts of interest to declare. This study received no funding from public, private, or not‐for‐profit sectors.

References

  1. Ann Hematol. 2003 Jan;82(1):57-60 - PubMed
  2. Cancer. 1984 Jul 15;54(2):303-7 - PubMed

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