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Spielman DB, Overdevest J, Gudis DA. Olfactory outcomes in the management of aspirin exacerbated respiratory disease related chronic rhinosinusitis. World J Otorhinolaryngol Head Neck Surg. 2020;6(4):207-213doi: 10.1016/j.wjorl.2020.07.001.
Spielman, D. B., Overdevest, J., & Gudis, D. A. (2020). Olfactory outcomes in the management of aspirin exacerbated respiratory disease related chronic rhinosinusitis. World journal of otorhinolaryngology - head and neck surgery, 6(4), 207-213. https://doi.org/10.1016/j.wjorl.2020.07.001
Spielman, Daniel B, et al. "Olfactory outcomes in the management of aspirin exacerbated respiratory disease related chronic rhinosinusitis." World journal of otorhinolaryngology - head and neck surgery vol. 6,4 (2020): 207-213. doi: https://doi.org/10.1016/j.wjorl.2020.07.001
Spielman DB, Overdevest J, Gudis DA. Olfactory outcomes in the management of aspirin exacerbated respiratory disease related chronic rhinosinusitis. World J Otorhinolaryngol Head Neck Surg. 2020 Aug 26;6(4):207-213. doi: 10.1016/j.wjorl.2020.07.001. eCollection 2020 Dec. PMID: 33336175; PMCID: PMC7729240.
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World J Otorhinolaryngol Head Neck Surg. 2020 Aug 26;6(4):207-213. doi: 10.1016/j.wjorl.2020.07.001. eCollection 2020 Dec.

Olfactory outcomes in the management of aspirin exacerbated respiratory disease related chronic rhinosinusitis.

World journal of otorhinolaryngology - head and neck surgery

Daniel B Spielman, Jonathan Overdevest, David A Gudis

Affiliations

  1. Department of Otolaryngology - Head and Neck Surgery, Columbia University Medical Center, New York, NY, 10032, USA.

PMID: 33336175 PMCID: PMC7729240 DOI: 10.1016/j.wjorl.2020.07.001

Abstract

Patients with aspirin exacerbated respiratory disease (AERD) experience a severe and recalcitrant form of chronic rhinosinusitis with nasal polyposis (CRSwNP) and asthma, which are exacerbated by aspirin/NSAID ingestion. As compared with aspirin-tolerant CRSwNP, patients with AERD experience more severe olfactory dysfunction, which is one of the key contributors to the observed decrease in quality of life (QOL) in this disease. The objective of this paper is to review the published olfactory outcomes observed with various treatment modalities.

© 2020 The Authors.

Keywords: AERD; Aspirin desensitization; Aspirin exacerbated respiratory disease; Endoscopic sinus surgery; NSAID; Olfaction; Samter's Triad; hyposmia

Conflict of interest statement

None.

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