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Skoda R, Nemes A, Bárczi G, et al. Prognosis and clinical characteristics of patients with early ventricular fibrillation in the 6-week guideline-offered time period: is it safe to wait 6 weeks with the assessment? (results from the VMAJOR-MI Registry). Quant Imaging Med Surg. 2021;11(1):402-409doi: 10.21037/qims-20-973.
Skoda, R., Nemes, A., Bárczi, G., Gajdácsi, J., Vágó, H., Ruzsa, Z., Édes, I. F., Szabó, L., Czimbalmos, C., Sydó, N., Dinya, E., Merkely, B., & Becker, D. (2021). Prognosis and clinical characteristics of patients with early ventricular fibrillation in the 6-week guideline-offered time period: is it safe to wait 6 weeks with the assessment? (results from the VMAJOR-MI Registry). Quantitative imaging in medicine and surgery, 11(1), 402-409. https://doi.org/10.21037/qims-20-973
Skoda, Réka, et al. "Prognosis and clinical characteristics of patients with early ventricular fibrillation in the 6-week guideline-offered time period: is it safe to wait 6 weeks with the assessment? (results from the VMAJOR-MI Registry)." Quantitative imaging in medicine and surgery vol. 11,1 (2021): 402-409. doi: https://doi.org/10.21037/qims-20-973
Skoda R, Nemes A, Bárczi G, Gajdácsi J, Vágó H, Ruzsa Z, Édes IF, Szabó L, Czimbalmos C, Sydó N, Dinya E, Merkely B, Becker D. Prognosis and clinical characteristics of patients with early ventricular fibrillation in the 6-week guideline-offered time period: is it safe to wait 6 weeks with the assessment? (results from the VMAJOR-MI Registry). Quant Imaging Med Surg. 2021 Jan;11(1):402-409. doi: 10.21037/qims-20-973. PMID: 33392039; PMCID: PMC7719948.
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Quant Imaging Med Surg. 2021 Jan;11(1):402-409. doi: 10.21037/qims-20-973.

Prognosis and clinical characteristics of patients with early ventricular fibrillation in the 6-week guideline-offered time period: is it safe to wait 6 weeks with the assessment? (results from the VMAJOR-MI Registry).

Quantitative imaging in medicine and surgery

Réka Skoda, Attila Nemes, György Bárczi, József Gajdácsi, Hajnalka Vágó, Zoltán Ruzsa, István F Édes, Liliána Szabó, Csilla Czimbalmos, Nóra Sydó, Elek Dinya, Béla Merkely, Dávid Becker

Affiliations

  1. Heart and Vascular Center, Semmelweis University, Budapest, Hungary.
  2. Department of Medicine, Albert Szent-Györgyi Clinical Center, Medical Faculty, University of Szeged, Szeged, Hungary.

PMID: 33392039 PMCID: PMC7719948 DOI: 10.21037/qims-20-973

Abstract

BACKGROUND: The most common, potentially fatal complication following an acute myocardial infarction (AMI) is early ventricular fibrillation (EVF). According to the guidelines, the assessment of implanting an implantable cardioverter defibrillator (ICD) is sufficient 6 weeks after the event, in patients with reduced left ventricular ejection fraction (LVEF), regardless of VF. The present study aimed to evaluate the 6-week prognosis of patients surviving an EVF. We divided the patients in two group based on their general condition at the time they left the hospital. We investigated the clinical characteristics of patients discharged in good general health but still dying within 6 weeks.

METHODS: The present study comprised 12,270 patients with AMI following their primary revascularization in the first 12 h of symptom onset. Five hundred and forty-seven of them suffered EVF due to the AMI. Clinical and 6-week mortality data were examined.

RESULTS: Poor general condition correlates with multiple comorbidities, higher troponin levels, more severe complications after the event. Patients leaving in good condition thought to be low risk, from dying. But low LVEF, high blood sugar, high cardiac biomarker level, poor renal function elevates the risk of dying within 6 weeks. However, there is no difference in clinical characteristics between EVF- cases and EVF+ cases in good condition who dies within 6 weeks.

CONCLUSIONS: According to our study we can select patients who are safe in the critical 6-week period and those who need closer follow-up despite leaving in good general condition.

2021 Quantitative Imaging in Medicine and Surgery. All rights reserved.

Keywords: Early ventricular fibrillation (EVF); acute myocardial infarction (AMI); prognosis

Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/qims-20-973). AN serves as an unpaid editorial board member of Quantitative

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