Display options
Cite
Fleit M, Volkman H, Alpern JD, et al. Impact of Anthelmintic Price Increases on Practice Patterns of Healthcare Providers Caring for Immigrant and Refugee Populations in the United States. Am J Trop Med Hyg. 2020;doi: 10.4269/ajtmh.20-0362.
Fleit, M., Volkman, H., Alpern, J. D., Lindrose, A. R., Stauffer, W., & Mitre, E. (2020). Impact of Anthelmintic Price Increases on Practice Patterns of Healthcare Providers Caring for Immigrant and Refugee Populations in the United States. The American journal of tropical medicine and hygiene, . https://doi.org/10.4269/ajtmh.20-0362
Fleit, Madeline, et al. "Impact of Anthelmintic Price Increases on Practice Patterns of Healthcare Providers Caring for Immigrant and Refugee Populations in the United States." The American journal of tropical medicine and hygiene vol. (2020). doi: https://doi.org/10.4269/ajtmh.20-0362
Fleit M, Volkman H, Alpern JD, Lindrose AR, Stauffer W, Mitre E. Impact of Anthelmintic Price Increases on Practice Patterns of Healthcare Providers Caring for Immigrant and Refugee Populations in the United States. Am J Trop Med Hyg. 2020 Dec 28; doi: 10.4269/ajtmh.20-0362. Epub 2020 Dec 28. PMID: 33372650; PMCID: PMC7866350.
Copy Download .nbib Format: NLM
Share it on

Am J Trop Med Hyg. 2020 Dec 28; doi: 10.4269/ajtmh.20-0362. Epub 2020 Dec 28.

Impact of Anthelmintic Price Increases on Practice Patterns of Healthcare Providers Caring for Immigrant and Refugee Populations in the United States.

The American journal of tropical medicine and hygiene

Madeline Fleit, Hannah Volkman, Jonathan D Alpern, Alyssa R Lindrose, William Stauffer, Edward Mitre

Affiliations

  1. Department of Medicine, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
  2. Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, Minnesota.
  3. HealthPartners Institute, HealthPartners Travel and Tropical Medicine Center, Minneapolis, Minnesota.
  4. Department of Microbiology and Immunology, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
  5. Center for Global Health and Social Responsibility, School of Public Health, University of Minnesota, Minneapolis, Minnesota.
  6. Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
  7. Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, Minnesota.

PMID: 33372650 PMCID: PMC7866350 DOI: 10.4269/ajtmh.20-0362

Abstract

In the United States, prices of long-established, generic anthelmintic medications have markedly risen. In the past decade, albendazole and mebendazole have increased in price by > 8,000%, whereas praziquantel has increased by > 500%. To determine the effect of these price increases on the practice patterns of healthcare providers, we conducted a cross-sectional electronic survey of clinics in the United States that primarily care for immigrant and refugee patient populations. Among 32 clinics, 53.1% reported that price increases impacted how providers diagnosed and treated helminth infections. A third (34.4%) of clinics reported that price increases have left them unable to treat known helminth infections. Other ways in which price increases impacted practice patterns included prescribing anthelmintics other than albendazole, mebendazole, or praziquantel when possible (34.4%); avoiding screening asymptomatic patients for helminth infections (15.6%); advising patients to acquire medications from another country (15.6%) or the patient's home country (9.4%); reducing anthelmintic dosing regimens to fewer pills (9.4%); and advising patients to purchase medications on the Internet (6.3%). These findings suggest price increases have negatively impacted the diagnosis and treatment of helminth infections in this population, and have resulted in the inability to treat known helminth infections. These findings have significant implications for the morbidity and mortality of infected individuals, as well as for public health in the United States.

References

  1. Vaccine. 2016 Jun 24;34(30):3549-55 - PubMed
  2. JAMA Intern Med. 2019 Jan 1;179(1):112-114 - PubMed
  3. Pediatr Rev. 2015 Aug;36(8):341-52; quiz 353-4 - PubMed
  4. Oncologist. 2013;18(4):381-90 - PubMed
  5. PLoS Negl Trop Dis. 2018 Jul 19;12(7):e0006370 - PubMed
  6. NCHS Data Brief. 2013 Apr;(119):1-8 - PubMed
  7. South Med J. 2009 Feb;102(2):139-44 - PubMed
  8. PLoS Negl Trop Dis. 2017 Sep 14;11(9):e0005794 - PubMed
  9. N Engl J Med. 2014 Nov 13;371(20):1859-62 - PubMed
  10. Health Aff (Millwood). 2009 May-Jun;28(3):827-34 - PubMed
  11. Infect Dis Clin North Am. 2019 Mar;33(1):135-151 - PubMed
  12. Am J Trop Med Hyg. 2017 Nov;97(5):1623-1628 - PubMed
  13. J Invest Dermatol. 2017 Dec;137(12):2491-2496 - PubMed
  14. PLoS Negl Trop Dis. 2008 Jun 25;2(6):e256 - PubMed
  15. J Oncol Pract. 2017 Mar;13(3):e240-e248 - PubMed
  16. Semin Hematol. 2018 Oct;55(4):185-188 - PubMed
  17. NCHS Data Brief. 2015 Jan;(184):1-8 - PubMed
  18. J Manag Care Pharm. 2007 Jul-Aug;13(6):506-14 - PubMed
  19. PLoS Negl Trop Dis. 2016 Aug 10;10(8):e0004910 - PubMed
  20. J Pharm Pract. 2018 Aug;31(4):399-402 - PubMed
  21. NCHS Data Brief. 2019 Mar;(333):1-8 - PubMed
  22. J Clin Oncol. 2014 Feb 1;32(4):306-11 - PubMed
  23. J Health Care Poor Underserved. 2011 Feb;22(1):24-49 - PubMed
  24. Pediatr Neurol. 2010 Sep;43(3):163-6 - PubMed
  25. Curr Diab Rep. 2017 Sep;17(9):71 - PubMed
  26. N Engl J Med. 2016 May 19;374(20):1904-7 - PubMed
  27. JAMA Dermatol. 2016 Feb;152(2):158-63 - PubMed
  28. Health Aff (Millwood). 2018 Oct;37(10):1578-1586 - PubMed
  29. Clin Infect Dis. 2017 Nov 13;65(11):1848-1852 - PubMed

Publication Types