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Tawfik SM, Azizov S, Elmasry MR, et al. Recent Advances in Nanomicelles Delivery Systems. Nanomaterials (Basel). 2020;11(1)doi: 10.3390/nano11010070.
Tawfik, S. M., Azizov, S., Elmasry, M. R., Sharipov, M., & Lee, Y. I. (2020). Recent Advances in Nanomicelles Delivery Systems. Nanomaterials (Basel, Switzerland), 11(1), . https://doi.org/10.3390/nano11010070
Tawfik, Salah M, et al. "Recent Advances in Nanomicelles Delivery Systems." Nanomaterials (Basel, Switzerland) vol. 11,1 (2020). doi: https://doi.org/10.3390/nano11010070
Tawfik SM, Azizov S, Elmasry MR, Sharipov M, Lee YI. Recent Advances in Nanomicelles Delivery Systems. Nanomaterials (Basel). 2020 Dec 30;11(1). doi: 10.3390/nano11010070. PMID: 33396938; PMCID: PMC7823398.
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Nanomaterials (Basel). 2020 Dec 30;11(1). doi: 10.3390/nano11010070.

Recent Advances in Nanomicelles Delivery Systems.

Nanomaterials (Basel, Switzerland)

Salah M Tawfik, Shavkatjon Azizov, Mohamed R Elmasry, Mirkomil Sharipov, Yong-Ill Lee

Affiliations

  1. Department of Materials Convergence and System Engineering, Changwon National University, Changwon 51140, Korea.
  2. Surfactant Laboratory, Department of Petrochemicals, Egyptian Petroleum Research Institute (EPRI), Nasr City, Cairo 11727, Egypt.
  3. Laboratory of Polysaccharide Chemistry, Institute of Bioorganic Chemistry, Uzbekistan Academy of Science, Tashkent 100125, Uzbekistan.

PMID: 33396938 PMCID: PMC7823398 DOI: 10.3390/nano11010070

Abstract

The efficient and selective delivery of therapeutic drugs to the target site remains the main obstacle in the development of new drugs and therapeutic interventions. Up until today, nanomicelles have shown their prospective as nanocarriers for drug delivery owing to their small size, good biocompatibility, and capacity to effectively entrap lipophilic drugs in their core. Nanomicelles are formed via self-assembly in aqueous media of amphiphilic molecules into well-organized supramolecular structures. Molecular weights and structure of the core and corona forming blocks are important properties that will determine the size of nanomicelles and their shape. Selective delivery is achieved via novel design of various stimuli-responsive nanomicelles that release drugs based on endogenous or exogenous stimulations such as pH, temperature, ultrasound, light, redox potential, and others. This review summarizes the emerging micellar nanocarriers developed with various designs, their outstanding properties, and underlying principles that grant targeted and continuous drug delivery. Finally, future perspectives, and challenges for nanomicelles are discussed based on the current achievements and remaining issues.

Keywords: drug delivery; fluorescence imaging; nanomicelles; spectroscopy; stimulus-responsive

References

  1. Mol Pharm. 2016 Nov 7;13(11):3934-3944 - PubMed
  2. Eur J Pharm Sci. 2016 Feb 15;83:184-202 - PubMed
  3. Biomater Sci. 2016 Aug 16;4(9):1318-27 - PubMed
  4. J Control Release. 2007 Jun 22;119(3):291-300 - PubMed
  5. Nanomedicine. 2016 Feb;12(2):269-86 - PubMed
  6. J Control Release. 2005 Jan 3;101(1-3):223-32 - PubMed
  7. Nat Nanotechnol. 2007 Dec;2(12):751-60 - PubMed
  8. J Nanosci Nanotechnol. 2015 Jul;15(7):4753-73 - PubMed
  9. Eur J Pharm Biopharm. 1999 Sep;48(2):101-11 - PubMed
  10. Acc Chem Res. 2017 Feb 21;50(2):281-292 - PubMed
  11. Angew Chem Int Ed Engl. 2005 Jan 7;44(3):409-12 - PubMed
  12. Pharmaceutics. 2020 Jul 20;12(7): - PubMed
  13. Angew Chem Int Ed Engl. 2014 May 5;53(19):4756-95 - PubMed
  14. ACS Appl Mater Interfaces. 2017 Aug 2;9(30):25152-25163 - PubMed
  15. Polymers (Basel). 2017 Oct 25;9(11): - PubMed
  16. Nanomedicine (Lond). 2007 Oct;2(5):669-80 - PubMed
  17. Photochem Photobiol. 2009 Jul-Aug;85(4):848-60 - PubMed
  18. Bioconjug Chem. 2010 Feb 17;21(2):208-13 - PubMed
  19. ACS Appl Mater Interfaces. 2009 Jul;1(7):1474-81 - PubMed
  20. Bioconjug Chem. 2005 Jan-Feb;16(1):122-30 - PubMed
  21. Bioconjug Chem. 2007 Jul-Aug;18(4):1131-9 - PubMed
  22. Colloids Surf B Biointerfaces. 2021 Jan;197:111382 - PubMed
  23. Mol Pharm. 2008 Jul-Aug;5(4):505-15 - PubMed
  24. Nano Lett. 2009 Feb;9(2):562-70 - PubMed
  25. Biomaterials. 2018 Sep;178:204-280 - PubMed
  26. Chem Rev. 2018 Jul 25;118(14):6844-6892 - PubMed
  27. J Control Release. 2010 Feb 25;142(1):40-6 - PubMed
  28. Carbohydr Polym. 2018 Feb 1;181:570-578 - PubMed
  29. Drug Deliv. 2002 Oct-Dec;9(4):253-8 - PubMed
  30. J Pharm Sci. 2003 Jul;92(7):1343-55 - PubMed
  31. Biomacromolecules. 2013 Aug 12;14(8):2772-80 - PubMed
  32. Int J Pharm. 2016 Jun 30;507(1-2):50-60 - PubMed
  33. Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):1968-1973 - PubMed
  34. J Pharm Pharmacol. 2016 Jun;68(6):751-61 - PubMed
  35. Int J Radiat Oncol Biol Phys. 2013 Jul 1;86(3):463-468 - PubMed
  36. J Pharm Sci. 1996 Jan;85(1):85-90 - PubMed
  37. Biomaterials. 2016 Apr;85:152-67 - PubMed
  38. Int J Biol Macromol. 2020 Feb 15;145:655-662 - PubMed
  39. Crit Rev Ther Drug Carrier Syst. 2003;20(5):357-403 - PubMed
  40. Front Pharmacol. 2018 Mar 08;9:202 - PubMed
  41. Nat Rev Drug Discov. 2008 Sep;7(9):771-82 - PubMed
  42. ACS Nano. 2019 May 28;13(5):5816-5825 - PubMed
  43. Nat Biotechnol. 2001 Apr;19(4):316-7 - PubMed
  44. Acta Biomater. 2010 Aug;6(8):3256-63 - PubMed
  45. Chem Rev. 2016 Feb 24;116(4):2602-63 - PubMed
  46. Pharm Res. 2001 Mar;18(3):323-8 - PubMed
  47. J Colloid Interface Sci. 2016 Aug 1;475:72-81 - PubMed
  48. Eur J Pharm Biopharm. 2009 Mar;71(3):431-44 - PubMed
  49. J Am Chem Soc. 2020 Feb 12;142(6):2709-2714 - PubMed
  50. Eur J Pharm Biopharm. 2015 Aug;94:501-12 - PubMed
  51. J Control Release. 2004 Apr 28;96(2):273-83 - PubMed
  52. Eur J Pharm Biopharm. 2014 Nov;88(3):670-82 - PubMed
  53. Colloids Surf B Biointerfaces. 2018 Jan 1;161:606-613 - PubMed
  54. Int J Biol Macromol. 2017 May;98:125-138 - PubMed
  55. Cancer Res. 2012 Apr 15;72(8):2100-10 - PubMed
  56. Nat Mater. 2013 Nov;12(11):991-1003 - PubMed
  57. Expert Opin Drug Deliv. 2010 Dec;7(12):1387-98 - PubMed
  58. Carbohydr Polym. 2019 Feb 15;206:309-318 - PubMed
  59. Sci Rep. 2018 Jul 2;8(1):9893 - PubMed
  60. ACS Appl Mater Interfaces. 2017 Aug 23;9(33):27587-27595 - PubMed
  61. Biomaterials. 2006 Aug;27(24):4356-73 - PubMed
  62. J Control Release. 2002 Nov 7;84(1-2):39-47 - PubMed
  63. Int J Biol Macromol. 2015 Sep;80:29-40 - PubMed
  64. Pharmaceutics. 2013 Mar 22;5(1):201-19 - PubMed
  65. NMR Biomed. 1999 Dec;12(8):495-504 - PubMed
  66. Nanomaterials (Basel). 2019 Apr 04;9(4): - PubMed
  67. Pharm Res. 2004 Nov;21(11):2001-8 - PubMed
  68. J Control Release. 2007 Oct 8;122(3):365-74 - PubMed
  69. Mol Pharm. 2004 Jul-Aug;1(4):317-30 - PubMed
  70. Bioconjug Chem. 2006 Jul-Aug;17(4):943-9 - PubMed
  71. Materials (Basel). 2014 Jan 28;7(2):805-875 - PubMed
  72. Macromol Biosci. 2012 Jul;12(7):926-36 - PubMed
  73. ACS Biomater Sci Eng. 2018 Jun 11;4(6):1928-1941 - PubMed
  74. Biomaterials. 2013 May;34(14):3647-57 - PubMed
  75. Int J Pharm. 2019 Jan 30;555:270-279 - PubMed
  76. J Am Chem Soc. 2019 Dec 11;141(49):19221-19225 - PubMed
  77. Biomaterials. 2010 May;31(13):3707-14 - PubMed
  78. Bioconjug Chem. 1992 Jul-Aug;3(4):295-301 - PubMed
  79. J Control Release. 2015 Apr 10;203:77-84 - PubMed
  80. Mol Pharm. 2014 Feb 3;11(2):375-81 - PubMed
  81. Toxicol Pathol. 2013;41(7):970-83 - PubMed
  82. ACS Appl Mater Interfaces. 2018 Mar 7;10(9):7798-7810 - PubMed
  83. Biomaterials. 2018 Apr;161:144-153 - PubMed
  84. J Biomed Nanotechnol. 2016 Dec;12(12):2083-96 - PubMed
  85. J Colloid Interface Sci. 2009 Jan 15;329(2):244-52 - PubMed
  86. Nanomaterials (Basel). 2020 Mar 02;10(3): - PubMed
  87. Macromol Rapid Commun. 2015 Oct;36(20):1841-9 - PubMed
  88. J R Soc Interface. 2009 Jun 6;6 Suppl 3:S325-39 - PubMed
  89. Science. 2002 Nov 29;298(5599):1759-62 - PubMed
  90. Drug Dev Ind Pharm. 2017 Nov;43(11):1846-1857 - PubMed
  91. J Control Release. 2005 Mar 21;103(2):405-18 - PubMed
  92. Sci Rep. 2017 Nov 22;7(1):16073 - PubMed
  93. ACS Appl Mater Interfaces. 2018 Jul 5;10(26):21847-21860 - PubMed
  94. J Am Chem Soc. 2017 Aug 16;139(32):10980-10983 - PubMed
  95. ACS Appl Mater Interfaces. 2015 Jan 28;7(3):2104-15 - PubMed
  96. J Drug Deliv. 2013;2013:340315 - PubMed
  97. J Control Release. 2012 May 10;159(3):312-23 - PubMed
  98. Mater Sci Eng C Mater Biol Appl. 2017 Aug 1;77:1068-1077 - PubMed
  99. J Control Release. 2010 Apr 2;143(1):136-42 - PubMed
  100. J Control Release. 2013 Oct 28;171(2):133-42 - PubMed
  101. J Am Chem Soc. 2005 Jul 20;127(28):9952-3 - PubMed
  102. ACS Appl Mater Interfaces. 2013 Dec 26;5(24):12895-904 - PubMed
  103. Carbohydr Polym. 2019 Jan 1;203:10-18 - PubMed
  104. Nanomedicine. 2010 Dec;6(6):714-29 - PubMed
  105. Biomacromolecules. 2019 Aug 12;20(8):3041-3056 - PubMed
  106. Mol Cancer Ther. 2014 Dec;13(12):2864-75 - PubMed
  107. Chem Rev. 2016 Feb 24;116(4):2170-243 - PubMed
  108. J Control Release. 2011 May 30;152(1):49-56 - PubMed
  109. J Control Release. 2001 Jul 10;75(1-2):69-81 - PubMed
  110. Nanomaterials (Basel). 2019 Jan 05;9(1): - PubMed
  111. J Control Release. 2006 Oct 27;115(3):322-34 - PubMed
  112. J Drug Target. 2006 Jul;14(6):343-55 - PubMed
  113. Nanomedicine. 2018 Apr;14(3):713-723 - PubMed
  114. Biomaterials. 2016 Mar;83:219-32 - PubMed
  115. Nat Rev Drug Discov. 2010 Aug;9(8):615-27 - PubMed
  116. ACS Nano. 2017 Dec 26;11(12):12276-12291 - PubMed
  117. Biomaterials. 2020 Feb;232:119702 - PubMed
  118. J Control Release. 2013 Apr 28;167(2):210-8 - PubMed
  119. Nanomedicine (Lond). 2010 Apr;5(3):485-505 - PubMed
  120. J Control Release. 2015 Jul 10;209:288-307 - PubMed
  121. Adv Exp Med Biol. 2016;880:365-84 - PubMed
  122. J Drug Target. 2017 Feb;25(2):140-148 - PubMed
  123. Chem Soc Rev. 2011 Mar;40(3):1761-76 - PubMed
  124. Nanoscale. 2013 Jan 7;5(1):231-8 - PubMed
  125. J Control Release. 2018 Feb 28;272:114-144 - PubMed
  126. Nanomedicine. 2015 Jan;11(1):175-84 - PubMed
  127. Biomaterials. 2005 Nov;26(33):6736-42 - PubMed
  128. ACS Nano. 2015 Jul 28;9(7):7195-206 - PubMed
  129. Org Biomol Chem. 2017 Jul 19;15(28):5867-5876 - PubMed
  130. J Am Chem Soc. 2009 Apr 8;131(13):4830-8 - PubMed
  131. J Control Release. 2005 Jun 2;104(3):477-88 - PubMed
  132. Biomaterials. 2019 Oct;217:119304 - PubMed
  133. Pharm Res. 2007 Jun;24(6):1029-46 - PubMed
  134. J Drug Target. 2002 Aug;10(5):429-37 - PubMed
  135. J Control Release. 2002 Aug 21;82(2-3):189-212 - PubMed
  136. ACS Appl Mater Interfaces. 2020 Mar 11;12(10):12109-12119 - PubMed
  137. Langmuir. 2004 Oct 12;20(21):9388-95 - PubMed
  138. J Mater Chem B. 2020 Mar 11;8(10):2115-2122 - PubMed
  139. Biochim Biophys Acta. 1994 Oct 12;1195(1):181-4 - PubMed
  140. Biol Pharm Bull. 2006 Sep;29(9):1790-8 - PubMed
  141. Colloids Surf B Biointerfaces. 2019 Jan 1;173:346-355 - PubMed
  142. Small. 2013 May 27;9(9-10):1521-32 - PubMed
  143. Colloids Surf B Biointerfaces. 2016 Feb 1;138:60-9 - PubMed
  144. Nat Mater. 2010 Feb;9(2):101-13 - PubMed
  145. J Microencapsul. 2013;30(7):701-8 - PubMed
  146. Chem Commun (Camb). 2014 Mar 25;50(24):3234-7 - PubMed
  147. Biomaterials. 2019 Jan;188:96-106 - PubMed
  148. Yakugaku Zasshi. 2008 Jun;128(6):941-50 - PubMed
  149. J Agric Food Chem. 2020 May 6;68(18):5249-5258 - PubMed
  150. Bioconjug Chem. 2018 Jun 20;29(6):1942-1949 - PubMed
  151. Angew Chem Int Ed Engl. 2003 Oct 6;42(38):4640-3 - PubMed
  152. Adv Drug Deliv Rev. 2003 Feb 10;55(2):199-215 - PubMed
  153. J Pharm Sci. 2009 Mar;98(3):795-811 - PubMed
  154. Biomaterials. 2014 Apr;35(13):4213-22 - PubMed
  155. Br J Cancer. 2005 Apr 11;92(7):1240-6 - PubMed
  156. Biomaterials. 2015 Jan;39:23-30 - PubMed
  157. J Control Release. 2005 Mar 21;103(2):341-53 - PubMed
  158. Proc Natl Acad Sci U S A. 2003 May 13;100(10):6039-44 - PubMed
  159. Biomaterials. 2020 Feb;232:119685 - PubMed
  160. Nanoscale. 2018 Jan 25;10(4):2115-2127 - PubMed
  161. Biointerphases. 2012 Dec;7(1-4):9 - PubMed
  162. ACS Biomater Sci Eng. 2018 Feb 12;4(2):566-575 - PubMed
  163. Eur J Pharm Biopharm. 2012 Oct;82(2):219-29 - PubMed
  164. Angew Chem Int Ed Engl. 2004 May 24;43(22):2959-62 - PubMed
  165. J Control Release. 2002 Aug 21;82(2-3):359-71 - PubMed
  166. ACS Appl Mater Interfaces. 2016 Feb;8(7):4347-56 - PubMed
  167. Drug Deliv. 2017 Nov;24(1):1170-1178 - PubMed
  168. Nanomedicine. 2005 Sep;1(3):193-212 - PubMed
  169. Eur J Pharm Biopharm. 2014 Oct;88(2):539-50 - PubMed
  170. Br J Cancer. 2008 Aug 5;99(3):392-7 - PubMed
  171. Pharm Res. 2007 Jan;24(1):1-16 - PubMed
  172. Cancer Res. 1991 Jun 15;51(12):3229-36 - PubMed
  173. Colloids Surf B Biointerfaces. 2014 Nov 1;123:364-86 - PubMed
  174. Macromol Rapid Commun. 2016 Jan;37(2):149-54 - PubMed
  175. Adv Mater. 2018 Jul;30(30):e1704490 - PubMed
  176. Int J Biol Macromol. 2020 Apr 15;149:809-818 - PubMed
  177. Adv Drug Deliv Rev. 2002 Oct 16;54(7):889-910 - PubMed
  178. J Control Release. 1999 Nov 1;62(1-2):115-27 - PubMed
  179. Nat Biotechnol. 1999 Nov;17(11):1101-4 - PubMed
  180. Biomacromolecules. 2004 May-Jun;5(3):818-21 - PubMed
  181. Int J Pharm. 2012 Apr 15;426(1-2):193-201 - PubMed
  182. Angew Chem Int Ed Engl. 2019 Oct 14;58(42):15120-15127 - PubMed

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