Eur J Hum Genet. 2021 May;29(5):726-735. doi: 10.1038/s41431-020-00791-9. Epub 2021 Jan 04.

The impact of needs-based education on the change of knowledge and attitudes towards medical genetics in medical students.

European journal of human genetics : EJHG

Paola Čargonja, Martina Mavrinac, Saša Ostojić, Nina Pereza

PMID: 33398082 PMCID: PMC8110770 DOI: 10.1038/s41431-020-00791-9

Abstract

In this research we aimed to (1) develop and validate a new questionnaire examining attitudes and knowledge towards medical genetics, (2) examine the knowledge and attitudes towards medical genetics in students of the Medical Faculty in Rijeka, Croatia and (3) evaluate the impact of education from the mandatory course Medical Genetics on the change of knowledge and attitudes. The study was conducted on 191 fifth- and sixth-year students of the Integrated Undergraduate and Graduate University Study of Medicine in the academic year 2019/2020. Students completed the validated online questionnaire anonymously and voluntarily. Fifth-year students completed the questionnaire twice (beginning/end of the course), while sixth-year students completed the questionnaire once, 3 months after completing the course. The education was carefully designed for medical students according to the CoreCompetences in Genetics for Health Professionals in Europe issued by the European Society of Human Genetics. Using the Kruskal-Wallis test, a statistically significant difference was found between fifth year before and after education and between the fifth year before education and sixth year for (a) total knowledge (P < 0.001), (b) total attitudes (P < 0.001) and (c) personal assessment of knowledge in medical genetics (P < 0.001). Moreover, positive attitudes were associated with higher levels of knowledge. In conclusion, our results emphasise the importance of needs-based education in medical genetics for medical students, which is indispensable for the increase in the level of knowledge and development of positive attitudes in order to provide better health care for patients with genetic disorders.

References

1. Wonkam A, Njamnshi AK, Angwafo FF III. Knowledge and attitudes concerning medical genetics amongst physicians and medical students in Cameroon (sub-Saharan Africa). Genet. 2006;8:331–8. - PubMed
2. Almomani BA, Al-Keilani MS, Al-Sawalha NA. Knowledge and views about genetics: a public-based cross-sectional study. Eur J Hum Genet. 2020;28:417–23. - PubMed
3. Hishiyama Y, Minari J, Suganuma N. The survey of public perception and general knowledge of genomic research and medicine in Japan conducted by the Japan Agency for Medical Research and Development. J Hum Genet. 2019;64:397–407. - PubMed
4. Dar-Nimrod I, MacNevin G, Godwin A, Lynch K, Magory Cohen T, Ganesan A, et al. Genetic knowledge within a national Australian sample: comparisons with other diverse populations. Public Health Genomics. 2018;21:133–43. - PubMed
5. Eum H, Lee M, Yoon J, Cho J, Lee ES, Choi KS, et al. Differences in attitudes toward genetic testing among the public, patients, and health-care professionals in Korea. Eur J Hum Genet. 2018;26:1432–40. - PubMed
6. Carver RB, Castéra J, Gericke N, Evangelista NA, El-Hani CN. Young adults’ belief in genetic determinism, and knowledge and attitudes towards modern genetics and genomics: The PUGGS Questionnaire. PLoS One. 2017;12:e0169808. - PubMed
7. Henneman L, Timmermans DR, van der Wal G. Public experiences, knowledge and expectations about medical genetics and the use of genetic information. Community Genet. 2004;7:33–43. - PubMed
8. Flouris A, Hawthorne G, Aitken M, Gaff C, Metcalfe SA. Development of a questionnaire for evaluating genetics education in general practice. J Community Genet. 2010;1:175–83. - PubMed
9. Baars MJ, Henneman L, Ten, Kate LP. Deficiency of knowledge of genetics and genetic tests among general practitioners, gynecologists, and pediatricians: a global problem. Genet Med. 2005;7:605–10. - PubMed
10. Jakobsen LB, Moum T, Heiberg A. Need of better knowledge of genetic tests among Norwegian physicians. Tidsskr Nor Laegeforen. 2000;120:2419–22. - PubMed
11. Kolb SE, Aguilar MC, Dinenberg M, Kaye CI. Genetics education for primary care providers in community health settings. J Community Health. 1999;24:45–59. - PubMed
12. Karuna N, Tragulpiankit P, Mahasirimongkol S, Chumnumwat S. Knowledge, attitude, and practice towards pharmacogenomics among hospital pharmacists in Thailand. Pharmacogenet Genomics. 2020;30:73–80. - PubMed
13. Alsaloumi L, Abdi A, Tosun Ö, Başgut B. Pharmacogenomics-based practice in North Cyprus: its adoption by pharmacists and their attitudes and knowledge. Int J Clin Pharm. 2019;41:1299–306. - PubMed
14. Albassam A, Alshammari S, Ouda G, Koshy S, Awad A. Knowledge, perceptions and confidence of physicians and pharmacists towards pharmacogenetics practice in Kuwait. PLoS One. 2018;13:e0203033. - PubMed
15. Formea CM, Nicholson WT, McCullough KB, Berg KD, Berg ML, Cunningham JL, et al. Development and evaluation of a pharmacogenomics educational program for pharmacists. Am J Pharm Educ. 2013;77:10. - PubMed
16. Coriolan S, Arikawe N, Moscati A, Zhou L, Dym S, Donmez S, et al. Pharmacy students’ attitudes and perceptions toward pharmacogenomics education. Am J Health Syst Pharm. 2019;76:836–45. - PubMed
17. Mahmutovic L, Akcesme B, Durakovic C, Akcesme FB, Maric A, Adilovic M, et al. Perceptions of students in health and molecular life sciences regarding pharmacogenomics and personalized medicine. Hum Genomics. 2018;12:50. - PubMed
18. Abdela OA, Bhagavathula AS, Gebreyohannes EA, Tegegn HG. Ethiopian health care professionals’ knowledge, attitude, and interests toward pharmacogenomics. Pharmgenomics Pers Med. 2017;10:279–85. - PubMed
19. Just KS, Steffens M, Swen JJ, Patrinos GP, Guchelaar HJ, Stingl JC. Medical education in pharmacogenomics-results from a survey on pharmacogenetic knowledge in healthcare professionals within the European pharmacogenomics clinical implementation project Ubiquitous Pharmacogenomics (U-PGx). Eur J Clin Pharmacol. 2017;73:1247–52. - PubMed
20. Lopes-Júnior LC, Carvalho Júnior PM, de Faria Ferraz VE, Nascimento LC, Van Riper M, Flória-Santos M. Genetic education, knowledge and experiences between nurses and physicians in primary care in Brazil: a cross-sectional study. Nurs Health Sci. 2017;19:66–74. - PubMed
21. Li J, Xu T, Yashar BM. Genetics educational needs in China: physicians’ experience and knowledge of genetic testing. Genet Med. 2015;17:757–60. - PubMed
22. Marzuillo C, De Vito C, D’Addario M, Santini P, D’Andrea E, Boccia A, et al. Are public health professionals prepared for public health genomics? A cross-sectional survey in Italy. BMC Health Serv Res. 2014;14:239. - PubMed
23. Nakamura S, Narimatsu H, Katayama K, Sho R, Yoshioka T, Fukao A, et al. Effect of genomics-related literacy on non-communicable diseases. J Hum Genet. 2017;62:839–46. - PubMed
24. Carroll JC, Rideout AL, Wilson BJ, Allanson JM, Blaine SM, Esplen MJ, et al. Genetic education for primary care providers: improving attitudes, knowledge, and confidence. Can Fam Physician. 2009;55:e92–9. - PubMed
25. Phadke SR, Agarwal S, Agarwal SS. Medical genetics education in India. Natl Med J India. 2002;15:363. - PubMed
26. Antoun J, Zgheib NK, Ashkar K. Education may improve the underutilization of genetic services by Middle Eastern primary care practitioners. Genet Test Mol Biomark. 2010;14:447–54. - PubMed
27. Watson EK, Shickle D, Qureshi N, Emery J, Austoker J. The ‘new genetics’ and primary care: GPs’ views on their role and their educational needs. Fam Pract. 1999;16:420–5. - PubMed
28. Kudzi W, Addy BS, Dzudzor B. Knowledge of pharmacogenetics among healthcare professionals and faculty members of health training institutions in Ghana. Ghana Med J. 2015;49:50–6. - PubMed
29. Li J, Huang W, Luo S, Lin Y, Duan R. Attitude of medical school students in China towards genetic testing and counseling issues in FXS. J Genet Couns. 2013;22:733–40. - PubMed
30. Ormond KE, Hudgins L, Ladd JM, Magnus DM, Greely HT, Cho MK. Medical and graduate students’ attitudes toward personal genomics. Genet Med. 2011;13:400–8. - PubMed
31. Bathurst L, Huang QR. A qualitative study of GPs’ views on modern genetics. Aust Fam Physician. 2006;35:462–4. - PubMed
32. Tomatir AG, Sorkun HC, Demirhan H, Akdağ B. Genetics and genetic counseling: practices and opinions of primary care physicians in Turkey. Genet Med. 2007;9:130–5. - PubMed
33. Olwi D, Merdad L, Ramadan E. Knowledge of genetics and attitudes toward genetic testing among college students in Saudi Arabia. Public Health Genomics. 2016;19:260–8. - PubMed
34. Douma KF, Smets EM, Allain DC. Non-genetic health professionals’ attitude towards, knowledge of and skills in discussing and ordering genetic testing for hereditary cancer. Fam Cancer. 2016;15:341–50. - PubMed
35. Talwar D, Tseng TS, Foster M, Xu L, Chen LS. Genetics/genomics education for nongenetic health professionals: a systematic literature review. Genet Med. 2017;19:725–32. - PubMed
36. Rubanovich CK, Cheung C, Mandel J, Bloss CS. Physician preparedness for big genomic data: a review of genomic medicine education initiatives in the United States. Hum Mol Genet. 2018;27:250–8. - PubMed
37. Burke S, Stone A, Bedward J, Thomas H, Farndon PA. A “neglected part of the curriculum” or “of limited use”? Views on genetics training by nongenetics medical trainees and implications for delivery. Genet Med. 2006;8:109–15. - PubMed
38. Eshg.org. European Society of Human Genetics. Core competences in genetics for health professionals in Europe. 2008. https://www.eshg.org/index.php?id=139 . Accessed 18 Jun 2020. - PubMed
39. Harvey EK, Fogel CE, Peyrot M, Christensen KD, Terry SF, McInerney J. Providers’ knowledge of genetics: a survey of 5915 individuals and families with genetic conditions. Genet Med. 2007;9:259–67. - PubMed
40. Calzone KA, Jenkins J, Bakos AD, Goldgar C, Rackover M, Jackson J, et al. Establishment of the genetic/genomic competency center for education. J Nurs Scholarsh. 2011;43:351–8. - PubMed
41. Calzone KA, Jenkins J, Bakos AD, Cashion A, Donaldson N.Genomic Nursing State of the Science Advisory Panel et al. A blueprint for genomic nursing science. J Nurs Scholarsh. 2013;45:96–104. - PubMed
42. Etchegary H, Cappelli M, Potter B, Vloet M, Graham I, Walker M, et al. Attitude and knowledge about genetics and genetic testing. Public Health Genomics. 2010;13:80–8. - PubMed
43. Lapham EV, Kozma C, Weiss JO, Benkendorf JL, Wilson MA. The gap between practice and genetics education of health professionals: HuGEM survey results. Genet Med. 2000;2:226–31. - PubMed

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