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Czajkowska A, Kaźmierczak-Siedlecka K, Jamioł-Milc D, et al. Gut microbiota and its metabolic potential. Eur Rev Med Pharmacol Sci. 2020;24(24):12971-12977doi: 10.26355/eurrev_202012_24201.
Czajkowska, A., Kaźmierczak-Siedlecka, K., Jamioł-Milc, D., Gutowska, I., & Skonieczna-Żydecka, K. (2020). Gut microbiota and its metabolic potential. European review for medical and pharmacological sciences, 24(24), 12971-12977. https://doi.org/10.26355/eurrev_202012_24201
Czajkowska, A, et al. "Gut microbiota and its metabolic potential." European review for medical and pharmacological sciences vol. 24,24 (2020): 12971-12977. doi: https://doi.org/10.26355/eurrev_202012_24201
Czajkowska A, Kaźmierczak-Siedlecka K, Jamioł-Milc D, Gutowska I, Skonieczna-Żydecka K. Gut microbiota and its metabolic potential. Eur Rev Med Pharmacol Sci. 2020 Dec;24(24):12971-12977. doi: 10.26355/eurrev_202012_24201. PMID: 33378048.
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Eur Rev Med Pharmacol Sci. 2020 Dec;24(24):12971-12977. doi: 10.26355/eurrev_202012_24201.

Gut microbiota and its metabolic potential.

European review for medical and pharmacological sciences

A Czajkowska, K Kaźmierczak-Siedlecka, D Jamioł-Milc, I Gutowska, K Skonieczna-Żydecka

Affiliations

  1. Department of Human Nutrition and Metabolomics, Pomeranian Medical University in Szczecin, Szczecin, Poland. [email protected].

PMID: 33378048 DOI: 10.26355/eurrev_202012_24201

Abstract

OBJECTIVE: The incidence of obesity and other metabolic-related diseases has been gradually increasing. Multiple genetic as well as environmental factors play a significant role in the pathogenesis of these entities. Currently, the involvement of gut microbiota in metabolic processes has been acknowledged. This paper focuses on obesity, type 2 diabetes, and nonalcoholic fatty liver disease regarding their link with microbiome structure and its function.

MATERIALS AND METHODS: We analyzed literature available in PubMed, Embase, and Google Scholar databases regarding a linkage of metabolic-associated diseases and gut microbiota RESULTS: Gut microbiota plays a significant role in host metabolism. Depending on its composition; however, it may contribute to the development of metabolic-associated diseases. In this context, not only composition of gut microbiota is important, but also its activity. Short-chain fatty acids or lipopolysaccharides are crucial metabolites involved in maintaining metabolic balance.

CONCLUSIONS: Gut microbiota malfunctions might potentially induce obesity, type 2 diabetes, and nonalcoholic fatty liver disease.

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