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HIV Res Clin Pract. 2020 Dec;21(6):182-190. doi: 10.1080/25787489.2020.1866846. Epub 2021 Jan 06.

Impact of extended-release niacin on immune activation in HIV-infected immunological non-responders on effective antiretroviral therapy.

HIV research & clinical practice

Bertrand Lebouché, Alexis Yero, Tao Shi, Omar Farnos, Joel Singer, Ido Kema, Cecilia T Costiniuk, Réjean Thomas, Marie-Josée Brouillette, Kim Engler, Jean-Pierre Routy, Mohammad-Ali Jenabian,

Affiliations

  1. Chronic Viral Illness Service, Division of Infectious Disease, Department of Medicine, Glen Site, McGill University Health Centre, Montreal, QC, Canada.
  2. Infectious Diseases and Immunity in Global Health, Research Institute of McGill University Health Centre, Montreal, QC, Canada.
  3. Department of Family Medicine, McGill University, Montreal, QC, Canada.
  4. Center for Outcome Research Evaluation, Research Institute of the McGill University Health Centre, Montreal, QC, Canada.
  5. Department of Biological Sciences and CERMO-FC Research Centre, University of Quebec at Montreal (UQAM), Montreal, QC, Canada.
  6. CIHR Canadian HIV Trials Network, Vancouver, BC, Canada.
  7. Department of Laboratory Medicine, University of Groningen, Groningen, The Netherlands.
  8. Department of Microbiology & Immunology, McGill University, Montreal, QC, Canada.
  9. Clinique médicale l'Actuel, Montreal, QC, Canada.
  10. Department of Psychiatry, McGill University, Montreal, QC, Canada.

PMID: 33403940 DOI: 10.1080/25787489.2020.1866846

[No abstract available.]

Keywords: HIV; IDO; immune activation; immunological non-responders; inflammation; kynurenine; niacin; tryptophan

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