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Said ER, Nagui NAER, Rashed LA, et al. Oxidative stress and the cholinergic system in non-segmental vitiligo: Effect of narrow band ultraviolet b. Photodermatol Photoimmunol Photomed. 2021;37(4):306-312doi: 10.1111/phpp.12653.
Said, E. R., Nagui, N. A. E. R., Rashed, L. A., & Mostafa, W. Z. (2021). Oxidative stress and the cholinergic system in non-segmental vitiligo: Effect of narrow band ultraviolet b. Photodermatology, photoimmunology & photomedicine, 37(4), 306-312. https://doi.org/10.1111/phpp.12653
Said, Eman Raafat, et al. "Oxidative stress and the cholinergic system in non-segmental vitiligo: Effect of narrow band ultraviolet b." Photodermatology, photoimmunology & photomedicine vol. 37,4 (2021): 306-312. doi: https://doi.org/10.1111/phpp.12653
Said ER, Nagui NAER, Rashed LA, Mostafa WZ. Oxidative stress and the cholinergic system in non-segmental vitiligo: Effect of narrow band ultraviolet b. Photodermatol Photoimmunol Photomed. 2021 Jul;37(4):306-312. doi: 10.1111/phpp.12653. Epub 2021 Jan 16. PMID: 33404131.
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Photodermatol Photoimmunol Photomed. 2021 Jul;37(4):306-312. doi: 10.1111/phpp.12653. Epub 2021 Jan 16.

Oxidative stress and the cholinergic system in non-segmental vitiligo: Effect of narrow band ultraviolet b.

Photodermatology, photoimmunology & photomedicine

Eman Raafat Said, Noha Abd El Rahim Nagui, Laila Ahmed Rashed, Wedad Zoheir Mostafa

Affiliations

  1. Dermatology Department, Faculty of medicine, Cairo University, Cairo, Egypt.
  2. Biochemistry Department, Faculty of Medicine, Cairo University, Cairo, Egypt.

PMID: 33404131 DOI: 10.1111/phpp.12653

Abstract

BACKGROUND: Despite exhaustive research, melanocyte disappearance and the evolution of vitiligo remain enigmatic, and although multi-factorial, oxidative stress appears as a major player. The role of cutaneous cholinergic system in vitiligo pathogenesis has also been reported in some studies.

OBJECTIVE: To evaluate and correlate the influence of phototherapy on cutaneous cholinergic system and oxidative stress in vitiligo.

METHODS: Acetyl choline (ACh), its receptors; nicotinic (nAChR) and muscarinic (mAChR); acetylcholine esterase (AChE) and H

RESULTS: Mean ACh and H

CONCLUSION: Cholinergic system is strongly involved in vitiligo pathogenesis through H

© 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Keywords: NB-UVB; acetyl choline; acetyl choline esterase; acetyl choline receptors; hydrogen peroxide

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