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Nat Prod Rep. 2021 Aug 01;38(8):1506-1517. doi: 10.1039/d0np00082e. Epub 2021 Jan 22.

Disclosing biosynthetic connections and functions of atypical angucyclinones with a fragmented C-ring.

Natural product reports

Andrey A Mikhaylov, Viktoria A Ikonnikova, Pavel N Solyev

Affiliations

  1. Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow, 117997, Russia. [email protected].

PMID: 33480893 DOI: 10.1039/d0np00082e

Abstract

This review on atypical angucyclinones possessing an aromatic cleavage of the C-ring covers literature between 1995 and early 2020.The unusual framework of the middle C-ring, "broken" as a result of biotransformations and oxidations in vivo and bearing an sp

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