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Int J Ment Health Syst. 2021 Jan 23;15(1):13. doi: 10.1186/s13033-021-00437-3.

Suicidal ideation, attempt, and its associated factors among HIV/AIDS patients in Africa: a systematic review and meta-analysis study.

International journal of mental health systems

Mogesie Necho, Mekonnen Tsehay, Yosef Zenebe

Affiliations

  1. Department of Psychiatry, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia. [email protected].
  2. Department of Psychiatry, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.

PMID: 33485362 PMCID: PMC7825170 DOI: 10.1186/s13033-021-00437-3

Abstract

BACKGROUND: Suicidal ideation and suicidal attempt are warning signs for and determine the prognosis of completed suicide. These suicidal behaviors are much more pronounced in people living with HIV/AIDS. Despite this, there is a scarcity of aggregate evidence in Africa. This study was therefore aimed to fill this gap.

METHODS: we extensively searched Psych-info, PubMed, Scopus, and EMBASE to obtain eligible studies. Further screening for a reference list of articles was also done. Meta XL package was used to extract data and the Stata-11 was also employed. Cochran's Q- and the Higgs I

RESULTS: The pooled prevalence of suicidal ideation was 21.7% (95% CI 16.80, 26.63). The pooled prevalence of suicidal ideation in Ethiopia, Nigeria, Uganda, and South Africa was 22.7%, 25.3%, 9.8%, and 18.05% respectively. The pooled prevalence of suicidal ideation was larger; 27.7% in studies that used Composite International Diagnostic Interview (CIDI) than Mini-international Neuropsychiatric Interview (MINI); 16.96%. Moreover, the prevalence of suicidal ideation in studies with a sample size of < 400 was 23.42% whereas it was 18.3% in studies with a sample size ≥ of 400 participants. The pooled prevalence of suicidal attempts in this study was 11.06% (95% CI 6.21, 15.92). A suicidal attempt was higher in Ethiopia (16.97%) and Nigeria (16.20%) than Uganda (3.51%). This pooled prevalence of suicidal attempt was higher among studies that used a smaller sample (< 400 participants) (15.5%) than studies that used a larger sample size (≥ 400 participants) (8.4%). The pooled prevalence of suicidal attempt was 3.75%, and 16.97% in studies that used MINI and CIDI respectively. Our narrative synthesis revealed that advanced stages of AIDS, co-morbid depression, perceived HIV stigma, and poor social support was among the factors strongly associated with suicidal ideation and attempt.

CONCLUSION: The pooled magnitude of suicidal ideation and attempt was high and factors like advanced stages of AIDS, co-morbid depression, perceived stigma, and poor social support were related to it. Clinicians should be geared towards this mental health problem of HIV patients during management.

Keywords: Africa; Meta-analysis; Suicide

References

  1. Soc Psychiatry Psychiatr Epidemiol. 2008 Sep;43(9):752-7 - PubMed
  2. PLoS One. 2018 Feb 22;13(2):e0192940 - PubMed
  3. Lancet. 2016 Mar 19;387(10024):1227-39 - PubMed
  4. J Affect Disord. 2006 Aug;94(1-3):269-75 - PubMed
  5. Perspect Psychiatr Care. 2019 Oct;55(4):538-545 - PubMed
  6. Subst Abuse Treat Prev Policy. 2020 Aug 24;15(1):63 - PubMed
  7. Syst Rev. 2015 Jan 01;4:1 - PubMed
  8. AIDS Care. 2010 Oct;22(10):1212-20 - PubMed
  9. J R Soc Med. 2005 Oct;98(10):459-63 - PubMed
  10. Afr J Psychiatry (Johannesbg). 2012 Mar;15(2):94-8 - PubMed
  11. Evid Based Dent. 2011 Dec;12(4):121-2 - PubMed
  12. Stat Med. 2002 Jun 15;21(11):1539-58 - PubMed
  13. Depress Res Treat. 2016;2016:8913160 - PubMed
  14. Glob Soc Welf. 2014 Mar;1(1):25-35 - PubMed
  15. Psychiatry J. 2017;2017:2301524 - PubMed
  16. Eur J Epidemiol. 2010 Sep;25(9):603-5 - PubMed
  17. J Affect Disord. 2017 Apr 01;212:117-127 - PubMed
  18. BMC Psychiatry. 2020 Jun 5;20(1):281 - PubMed
  19. BMC Psychiatry. 2012 Jun 18;12:63 - PubMed
  20. BMC Psychiatry. 2017 May 4;17(1):163 - PubMed
  21. AIDS Care. 2005 Jul;17(5):550-7 - PubMed
  22. Depress Res Treat. 2015;2015:609172 - PubMed
  23. J Int Assoc Physicians AIDS Care (Chic). 2011 Mar-Apr;10(2):89-96 - PubMed
  24. J Affect Disord. 2019 Feb 15;245:82-90 - PubMed
  25. Syst Rev. 2018 Dec 12;7(1):230 - PubMed
  26. Psychiatr Q. 2019 Dec;90(4):829-842 - PubMed
  27. Arch Public Health. 2014 Nov 10;72(1):39 - PubMed
  28. J Infect Dis. 2013 Mar;207 Suppl 1:S1-6 - PubMed
  29. Afr J AIDS Res. 2016 Sep;15(3):227-32 - PubMed
  30. Am J Psychiatry. 1971 Mar;127(9):1199-204 - PubMed
  31. Trop Doct. 2016 Oct;46(4):211-215 - PubMed
  32. BMC Public Health. 2014 Jun 14;14:606 - PubMed
  33. Psychiatry Clin Neurosci. 2014 Feb;68(2):96-109 - PubMed
  34. BMC Public Health. 2017 Jun 2;17(1):542 - PubMed
  35. AIDS Care. 2012;24(7):843-5 - PubMed
  36. Psychol Med. 2018 Mar;48(4):554-565 - PubMed
  37. PLoS One. 2019 Nov 5;14(11):e0224371 - PubMed
  38. Annu Rev Psychol. 2008;59:537-63 - PubMed
  39. AIDS Care. 2008 Sep;20(8):917-24 - PubMed
  40. Epidemiology. 2008 Jan;19(1):94-100 - PubMed
  41. Arch Suicide Res. 2015;19(1):103-16 - PubMed
  42. Psychiatr Q. 2020 Dec;91(4):1291-1304 - PubMed
  43. AIDS Patient Care STDS. 2009 Jun;23(6):469-75 - PubMed
  44. Healthc Policy. 2006 Nov;2(2):76-89 - PubMed
  45. Psychol Sci. 2017 Nov;28(11):1547-1562 - PubMed

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