Mindfulness (N Y). 2020 Apr;11(4):905-916. doi: 10.1007/s12671-019-01299-0. Epub 2020 Jan 14.
Psychological Processes and Symptom Outcomes in Mindfulness-Based Stress Reduction for Cancer Survivors: A Pilot Study.
Mindfulness
Kelly Chinh, Catherine E Mosher, Linda F Brown, Kathleen A Beck-Coon, Kurt Kroenke, Shelley A Johns
Affiliations
Affiliations
- Department of Psychology, Indiana University-Purdue University Indianapolis, Indianapolis, IN.
- Department of Medicine, Indiana University School of Medicine, Indianapolis, IN.
- Center for Health Services Research, Regenstrief Institute, Inc., Indianapolis, IN.
PMID: 33456623
PMCID: PMC7810211 DOI: 10.1007/s12671-019-01299-0
Abstract
OBJECTIVES: Growing evidence supports the efficacy of mindfulness-based interventions for symptoms in cancer survivors. Identifying theory-based psychological processes underlying their effects on symptoms would inform research to enhance their efficacy and cost-effectiveness. We conducted secondary analyses examining the effect of mindfulness-based stress reduction (MBSR) for cancer-related fatigue on mindfulness facets, self-compassion, and psychological inflexibility. We also examined whether changes in these processes were associated with the symptom outcomes of fatigue interference, sleep disturbance, and emotional distress.
METHODS: Thirty-five persistently fatigued cancer survivors (94% female, 77% breast cancer survivors) were randomized to either MBSR for cancer-related fatigue or a waitlist control (WC) condition. Self-report measures were administered at pre-intervention, post-intervention, and 1-month follow-up. Then the WC group received MBSR and completed a post-intervention follow-up.
RESULTS: Linear mixed modeling analyses of the first three time points showed steady increases over time for certain mindfulness facets (observing, acting with awareness, and nonjudging) and self-compassion in favor of the MBSR group. When analyzing pre- and post-intervention data across study conditions, none of the psychological processes predicted change in fatigue interference. However, increased nonjudging was associated with decreased sleep disturbance (
CONCLUSIONS: Results point to specific psychological processes that may be targeted to maximize the efficacy of future MBSR interventions for cancer survivors.
Keywords: cancer; fatigue; mindfulness-based stress reduction; psychological flexibility; self-compassion
Conflict of interest statement
Conflict of Interest The authors declare that they have no conflict of interest.
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