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Pasqualetto MC, Sorbo MD, Vitiello M, et al. Pulmonary Hypertension in COVID-19 Pneumoniae: It Is Not Always as It Seems. Eur J Case Rep Intern Med. 2020;7(12):002160doi: 10.12890/2020_002160.
Pasqualetto, M. C., Sorbo, M. D., Vitiello, M., Ferrara, C., Scevola, M., Pantalone, F., Gelain, F., Aloi, C., Nizzetto, M., & Rigo, F. (2020). Pulmonary Hypertension in COVID-19 Pneumoniae: It Is Not Always as It Seems. European journal of case reports in internal medicine, 7(12), 002160. https://doi.org/10.12890/2020_002160
Pasqualetto, Maria Cristina, et al. "Pulmonary Hypertension in COVID-19 Pneumoniae: It Is Not Always as It Seems." European journal of case reports in internal medicine vol. 7,12 (2020): 002160. doi: https://doi.org/10.12890/2020_002160
Pasqualetto MC, Sorbo MD, Vitiello M, Ferrara C, Scevola M, Pantalone F, Gelain F, Aloi C, Nizzetto M, Rigo F. Pulmonary Hypertension in COVID-19 Pneumoniae: It Is Not Always as It Seems. Eur J Case Rep Intern Med. 2020 Dec 11;7(12):002160. doi: 10.12890/2020_002160. eCollection 2020. PMID: 33457379; PMCID: PMC7806283.
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Eur J Case Rep Intern Med. 2020 Dec 11;7(12):002160. doi: 10.12890/2020_002160. eCollection 2020.

Pulmonary Hypertension in COVID-19 Pneumoniae: It Is Not Always as It Seems.

European journal of case reports in internal medicine

Maria Cristina Pasqualetto, Maria Domenica Sorbo, Maria Vitiello, Chiara Ferrara, Moreno Scevola, Fabio Pantalone, Fabio Gelain, Claudio Aloi, Manuele Nizzetto, Fausto Rigo

Affiliations

  1. Division of Cardiology, Dolo Hospital AULSS 3, Venice, Italy.
  2. Non-Critical COVID Area in Internal Medicine, Dolo Hospital AULSS 3, Venice, Italy.
  3. Division of Radiology and Diagnostic Imaging, Dolo Hospital AULSS 3, Venice, Italy.
  4. Sub-Intensive Care COVID Unit in Pneumology, Dolo Hospital AULSS 3, Venice, Italy.

PMID: 33457379 PMCID: PMC7806283 DOI: 10.12890/2020_002160

Abstract

A patient affected by COVID-19 pneumonia may develop pulmonary hypertension (PH) and secondary right ventricular (RV) involvement, due to lung parenchymal and interstitial damage and altered pulmonary haemodynamics, even in non-advanced phases of the disease. This is a consequence of hypoxic vasoconstriction of the pulmonary circulation, the use of positive end-expiratory pressure (PEEP) in mechanical ventilation, pulmonary endothelial injury, and local inflammatory thrombotic and/or thromboembolic processes. We report the case of a young man admitted with a diagnosis of COVID-19 pneumoniae with PH unrelated to viral infection and in whom partial anomalous pulmonary venous drainage (PAPVD) was eventually diagnosed.

LEARNING POINTS: COVID-19 patients, even if previously well, can have pulmonary hypertension due to other causes.The cause of pulmonary hypertension should always be sought and not assumed, even in COVID-19 patients.

© EFIM 2020.

Keywords: COVID-19; partial anomalous pulmonary venous drainage; pulmonary hypertension; right ventricular involvement

Conflict of interest statement

Conflicts of Interests: The Authors declare that there are no competing interests.

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