Display options
Cite
Longbottom C, Vernon B, Perfect E, et al. Initial investigations of a novel bioluminescence method for imaging dental demineralization. Clin Exp Dent Res. 2021;7(5):786-794doi: 10.1002/cre2.402.
Longbottom, C., Vernon, B., Perfect, E., Haughey, A. M., Christie, A., & Pitts, N. (2021). Initial investigations of a novel bioluminescence method for imaging dental demineralization. Clinical and experimental dental research, 7(5), 786-794. https://doi.org/10.1002/cre2.402
Longbottom, Christopher, et al. "Initial investigations of a novel bioluminescence method for imaging dental demineralization." Clinical and experimental dental research vol. 7,5 (2021): 786-794. doi: https://doi.org/10.1002/cre2.402
Longbottom C, Vernon B, Perfect E, Haughey AM, Christie A, Pitts N. Initial investigations of a novel bioluminescence method for imaging dental demineralization. Clin Exp Dent Res. 2021 Oct;7(5):786-794. doi: 10.1002/cre2.402. Epub 2021 Jan 28. PMID: 33507620; PMCID: PMC8543456.
Copy Download .nbib Format: NLM
Share it on

Clin Exp Dent Res. 2021 Oct;7(5):786-794. doi: 10.1002/cre2.402. Epub 2021 Jan 28.

Initial investigations of a novel bioluminescence method for imaging dental demineralization.

Clinical and experimental dental research

Christopher Longbottom, Bruce Vernon, Emma Perfect, Anne-Marie Haughey, Adam Christie, Nigel Pitts

Affiliations

  1. Dental Innovation and Impact, King's College London, London, UK.
  2. Calcivis, Nine Edinburgh BioQuarter, Edinburgh, UK.
  3. LUX Assure Ltd, Heriot Watt Research Park, Edinburgh, UK.
  4. Fraunhofer Centre for Applied Photonics, The Technology and Innovation Centre, Glasgow, UK.

PMID: 33507620 PMCID: PMC8543456 DOI: 10.1002/cre2.402

Abstract

OBJECTIVES: In this in vitro study, a bioluminescent marker was investigated for its potential to illuminate the assessment of dental caries and dental erosion, which are significant clinical and public health problems, through its binding of those ions, notably Ca

MATERIALS AND METHODS: The light output from the selected bioluminescent marker was investigated in several experiments, including: (a)contact with a range of Ca

RESULTS: The results of: experiment (a) showed that the light output from the marker increases with increasing Ca

CONCLUSIONS: These results demonstrate the ability of a novel bioluminescence technology to image Ca

© 2021 The Authors. Clinical and Experimental Dental Research published by John Wiley & Sons Ltd.

Keywords: activity; calcium; caries; luminescence

References

  1. Caries Res. 1999 Jul-Aug;33(4):261-6 - PubMed
  2. Int Dent J. 1991 Apr;41(2):111-6 - PubMed
  3. J La Dent Assoc. 1974 Winter;32(3):7-13 - PubMed
  4. Monogr Oral Sci. 2009;21:52-62 - PubMed
  5. Caries Res. 1997;31(2):103-10 - PubMed
  6. Br Dent J. 1999 Feb 13;186(3):115-8 - PubMed
  7. J Dent Res. 1954 Apr;33(2):231-44 - PubMed
  8. J Dent Res. 1981 Feb;60(2):120-2 - PubMed
  9. Photochem Photobiol. 2001 Nov;74(5):656-69 - PubMed
  10. J Natl Cancer Inst. 1993 Mar 17;85(6):443-56 - PubMed
  11. Caries Res. 1991;25(5):335-40 - PubMed
  12. Caries Res. 1978;12(2):69-75 - PubMed
  13. Clin Exp Dent Res. 2021 Oct;7(5):786-794 - PubMed
  14. Clin Oral Investig. 2014 Sep;18(7):1757-62 - PubMed
  15. Aust N Z J Surg. 1991 May;61(5):340-8 - PubMed
  16. Br J Nutr. 1989 Sep;62(2):451-64 - PubMed
  17. J Dent Res. 2004;83 Spec No C:C80-3 - PubMed
  18. Caries Res. 1995;29(1):2-7 - PubMed
  19. Zahnarztl Prax. 1985 Jan 12;36(1):17-8 - PubMed
  20. Arch Oral Biol. 1997 Sep;42(9):657-63 - PubMed

Publication Types

Grant support