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Sci Rep. 2021 Jan 28;11(1):2587. doi: 10.1038/s41598-021-82351-9.

Diagnostic performance of cone-beam computed tomography for scaphoid fractures: a systematic review and diagnostic meta-analysis.

Scientific reports

Ta-Wei Yang, Yen-Yue Lin, Shih-Chang Hsu, Karen Chia-Wen Chu, Chih-Wei Hsiao, Chin-Wang Hsu, Chyi-Huey Bai, Cheng-Kuang Chang, Yuan-Pin Hsu

Affiliations

  1. Department of Emergency Medicine, Taoyuan Armed Forces General Hospital, Taoyuan, Taiwan.
  2. National Defense Medical Center, Taipei, Taiwan.
  3. Emergency Department, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
  4. Department of Emergency, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
  5. Department of Orthopedic Surgery, Taoyuan Armed Forces General Hospital, Taoyuan, Taiwan.
  6. Department of Public Health, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
  7. Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
  8. Emergency Department, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan. [email protected].
  9. Department of Emergency, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. [email protected].
  10. Research Center of Big Data and Meta-Analysis, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan. [email protected].

PMID: 33510347 PMCID: PMC7843979 DOI: 10.1038/s41598-021-82351-9

Abstract

Scaphoid fractures are the most common carpal fractures. Diagnosing scaphoid fractures is challenging. Recently, cone-beam computed tomography (CBCT) has been shown to be a promising strategy for diagnosing scaphoid fractures. The diagnostic performance of CBCT remains inconclusive in the literature. Through a systematic review and meta-analysis, our study aims to determine the diagnostic performance of CBCT for diagnosing scaphoid fractures. Five databases were searched up to March 25, 2020. We included prospective and retrospective studies describing the diagnostic accuracy of CBCT for scaphoid fractures in adult patients. QUADAS-2 tool was used to assess the quality of the included studies. Four studies (nā€‰=ā€‰350) were included in the meta-analysis. Three of the four studies had high bias risk. The result showed that CBCT had a pooled sensitivity of 0.88 and a pooled specificity of 0.99 for scaphoid fracture diagnosis. The heterogeneities of sensitivity and specificity were substantial. The area under the summary receiver operating characteristic curve was 0.98. No significant publication bias was observed. The result suggested that the diagnostic performance of CBCT for scaphoid fracture was excellent. The certainty of current evidence is low. Further well-designed studies with large sample sizes are warranted to confirm this finding.

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