Display options
Cite
Deng C, Liu Y, Xu M, et al. Exploiting an intramolecular Diels-Alder cyclization/dehydro-aromatization sequence for the total syntheses of ellipticines and calothrixin B. Org Biomol Chem. 2021;19(6):1395-1403doi: 10.1039/d0ob02527e.
Deng, C., Liu, Y., Xu, M., Xie, K., & Liu, S. (2021). Exploiting an intramolecular Diels-Alder cyclization/dehydro-aromatization sequence for the total syntheses of ellipticines and calothrixin B. Organic & biomolecular chemistry, 19(6), 1395-1403. https://doi.org/10.1039/d0ob02527e
Deng, Chengdan, et al. "Exploiting an intramolecular Diels-Alder cyclization/dehydro-aromatization sequence for the total syntheses of ellipticines and calothrixin B." Organic & biomolecular chemistry vol. 19,6 (2021): 1395-1403. doi: https://doi.org/10.1039/d0ob02527e
Deng C, Liu Y, Xu M, Xie K, Liu S. Exploiting an intramolecular Diels-Alder cyclization/dehydro-aromatization sequence for the total syntheses of ellipticines and calothrixin B. Org Biomol Chem. 2021 Feb 18;19(6):1395-1403. doi: 10.1039/d0ob02527e. PMID: 33491728.
Copy Download .nbib Format: NLM
Share it on

Org Biomol Chem. 2021 Feb 18;19(6):1395-1403. doi: 10.1039/d0ob02527e.

Exploiting an intramolecular Diels-Alder cyclization/dehydro-aromatization sequence for the total syntheses of ellipticines and calothrixin B.

Organic & biomolecular chemistry

Chengdan Deng, Yuancui Liu, Mei Xu, Kaiqiang Xie, Sheng Liu

Affiliations

  1. State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China. [email protected] and Key Laboratory of Chemistry for Natural Products of Guizhou Province, Chinese Academy of Sciences, Guiyang 550014, China. [email protected].
  2. Key Laboratory of Chemistry for Natural Products of Guizhou Province, Chinese Academy of Sciences, Guiyang 550014, China. [email protected].

PMID: 33491728 DOI: 10.1039/d0ob02527e

Abstract

The tetracyclic and pentacyclic skeletons of pyrido and quinolinocarbazole alkaloids have been synthesized via a unified strategy. The prominent key step involved a Diels-Alder intramolecular cyclization/dehydro-aromatization sequence. From these carbazole-lactam cores, linear syntheses have been developed for ellipticines and calothrixin B.

Publication Types