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Narita K, Hoshide S, Kario K. Relationship Between Home Blood Pressure and the Onset Season of Cardiovascular Events: The J-HOP Study (Japan Morning Surge-Home Blood Pressure). Am J Hypertens. 2021;34(7):729-736doi: 10.1093/ajh/hpab016.
Narita, K., Hoshide, S., & Kario, K. (2021). Relationship Between Home Blood Pressure and the Onset Season of Cardiovascular Events: The J-HOP Study (Japan Morning Surge-Home Blood Pressure). American journal of hypertension, 34(7), 729-736. https://doi.org/10.1093/ajh/hpab016
Narita, Keisuke, et al. "Relationship Between Home Blood Pressure and the Onset Season of Cardiovascular Events: The J-HOP Study (Japan Morning Surge-Home Blood Pressure)." American journal of hypertension vol. 34,7 (2021): 729-736. doi: https://doi.org/10.1093/ajh/hpab016
Narita K, Hoshide S, Kario K. Relationship Between Home Blood Pressure and the Onset Season of Cardiovascular Events: The J-HOP Study (Japan Morning Surge-Home Blood Pressure). Am J Hypertens. 2021 Aug 09;34(7):729-736. doi: 10.1093/ajh/hpab016. PMID: 33493266.
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Am J Hypertens. 2021 Aug 09;34(7):729-736. doi: 10.1093/ajh/hpab016.

Relationship Between Home Blood Pressure and the Onset Season of Cardiovascular Events: The J-HOP Study (Japan Morning Surge-Home Blood Pressure).

American journal of hypertension

Keisuke Narita, Satoshi Hoshide, Kazuomi Kario

Affiliations

  1. Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan.
  2. Department of Cardiology, Karatsu Red Cross Hospital, Saga, Japan.

PMID: 33493266 DOI: 10.1093/ajh/hpab016

Abstract

BACKGROUND: The incidence of cardiovascular disease (CVD) increases during winter. The risk that elevated home blood pressure (BP) poses for CVD events that occur in each of 4 seasons is unclear. We conducted a post hoc analysis using the dataset from a nationwide cohort, the Japan Morning Surge-Home Blood Pressure (J-HOP) study, to assess the association between home BP and winter-onset CVD events.

METHODS: J-HOP participants who had cardiovascular risks conducted morning and evening home BP measurements for a 14-day period and were followed-up for the occurrence of CVD events.

RESULTS: We analyzed 4,258 participants (mean age 64.9 years; 47% male; 92% hypertensives) who were followed-up for an average of 6.2 ± 3.8 years (26,295 person-years). We divided the total of 269 CVD events (10.2/1,000 person-years) by the season of onset as follows: 82 in the winter and 187 in the other seasons (spring, summer, and autumn). In the Cox models adjusted for covariates and the season when home BPs were measured at baseline, morning home systolic BP (SBP) was associated with both winter-onset and other season-onset CVD events: hazard ratio (HR) for winter 1.22, 95% confidence interval (CI) 1.06-1.42 per 10 mm Hg; HR for other seasons 1.11, 95% CI 1.00-1.23. Evening home SBP was associated with the other season-onset CVD events (HR 1.20, 95% CI 1.08-1.33 per 10 mm Hg), but not with the winter-onset CVD events.

CONCLUSIONS: Our findings indicate that compared with evening home BP, morning home BP might be a superior predictor of winter-onset CVD events.

© American Journal of Hypertension, Ltd 2021. All rights reserved. For Permissions, please email: [email protected].

Keywords: blood pressure; home blood pressure; hypertension; morning home blood pressure; winter-onset cardiovascular event

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