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Song H, Kim HJ, Park KN, et al. Which Out-of-Hospital Cardiac Arrest Patients without ST-Segment Elevation Benefit from Early Coronary Angiography? Results from the Korean Hypothermia Network Prospective Registry. J Clin Med. 2021;10(3)doi: 10.3390/jcm10030439.
Song, H., Kim, H. J., Park, K. N., Kim, S. H., Kim, W. Y., Lee, B. K., Cho, I. S., Lee, J. H., Youn, C. S., & On Behalf Of The Korean Hypothermia Network Investigators. (2021). Which Out-of-Hospital Cardiac Arrest Patients without ST-Segment Elevation Benefit from Early Coronary Angiography? Results from the Korean Hypothermia Network Prospective Registry. Journal of clinical medicine, 10(3), . https://doi.org/10.3390/jcm10030439
Song, Hwan, et al. "Which Out-of-Hospital Cardiac Arrest Patients without ST-Segment Elevation Benefit from Early Coronary Angiography? Results from the Korean Hypothermia Network Prospective Registry." Journal of clinical medicine vol. 10,3 (2021). doi: https://doi.org/10.3390/jcm10030439
Song H, Kim HJ, Park KN, Kim SH, Kim WY, Lee BK, Cho IS, Lee JH, Youn CS, On Behalf Of The Korean Hypothermia Network Investigators. Which Out-of-Hospital Cardiac Arrest Patients without ST-Segment Elevation Benefit from Early Coronary Angiography? Results from the Korean Hypothermia Network Prospective Registry. J Clin Med. 2021 Jan 23;10(3). doi: 10.3390/jcm10030439. PMID: 33498728; PMCID: PMC7865270.
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J Clin Med. 2021 Jan 23;10(3). doi: 10.3390/jcm10030439.

Which Out-of-Hospital Cardiac Arrest Patients without ST-Segment Elevation Benefit from Early Coronary Angiography? Results from the Korean Hypothermia Network Prospective Registry.

Journal of clinical medicine

Hwan Song, Hyo Joon Kim, Kyu Nam Park, Soo Hyun Kim, Won Young Kim, Byung Kook Lee, In Soo Cho, Jae Hoon Lee, Chun Song Youn, On Behalf Of The Korean Hypothermia Network Investigators

Affiliations

  1. Department of Emergency Medicine, Seoul St. Mary Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
  2. Department of Emergency Medicine, Eunpyeong St. Mary Hospital, College of Medicine, The Catholic University of Korea, Seoul 03312, Korea.
  3. Asan Medical Center, Department of Emergency Medicine, Ulsan University College of Medicine, Seoul 05505, Korea.
  4. Department of Emergency Medicine, Chonnam National University Medical School, Gwangju 61469, Korea.
  5. Department of Emergency Medicine, Hanil General Hospital, Korea Electric Power Medical Corporation, Seoul 01450, Korea.
  6. Department of Emergency Medicine, Dong-A University College of Medicine, Busan 49201, Korea.

PMID: 33498728 PMCID: PMC7865270 DOI: 10.3390/jcm10030439

Abstract

The effect of early coronary angiography (CAG) in out-of-hospital cardiac arrest (OHCA) patients without ST-elevation (STE) is still controversial. It is not known which subgroups of patients without STE are the most likely to benefit. The objective of this study was to evaluate the association between emergency CAG and neurologic outcomes and identify subgroups with improved outcomes when emergency CAG was performed. This prospective, multicenter, observational cohort study was based on data from the Korean Hypothermia Network prospective registry (KORHN-PRO) 1.0. Adult OHCA patients who were treated with targeted temperature management (TTM) without any obvious extracardiac cause were included. Patients were dichotomized into early CAG (≤24 h) and no early CAG (>24 h or not performed) groups. High-risk patients were defined as having the Global Registry of Acute Coronary Events (GRACE) score > 140, time from collapse to return of spontaneous circulation (ROSC) > 30 min, lactate level > 7.0 mmol/L, arterial pH < 7.2, cardiac enzyme elevation and ST deviation. The primary outcome was good neurologic outcome at 6 months after OHCA. Of the 1373 patients from the KORHN-PRO 1.0 database, 678 patients met the inclusion criteria. The early CAG group showed better neurologic outcomes at 6 months after cardiac arrest (CA) (adjusted odds ratio: 2.21 (1.27-3.87),

Keywords: cardiopulmonary resuscitation; coronary angiography; out-of-hospital cardiac arrest; outcome

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