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Silva Dos Santos J, Gonçalves Cirino JP, de Oliveira Carvalho P, et al. The Pharmacological Action of Kaempferol in Central Nervous System Diseases: A Review. Front Pharmacol. 2021;11:565700doi: 10.3389/fphar.2020.565700.
Silva Dos Santos, J., Gonçalves Cirino, J. P., de Oliveira Carvalho, P., & Ortega, M. M. (2020). The Pharmacological Action of Kaempferol in Central Nervous System Diseases: A Review. Frontiers in pharmacology, 11565700. https://doi.org/10.3389/fphar.2020.565700
Silva Dos Santos, Jéssica, et al. "The Pharmacological Action of Kaempferol in Central Nervous System Diseases: A Review." Frontiers in pharmacology vol. 11 (2020): 565700. doi: https://doi.org/10.3389/fphar.2020.565700
Silva Dos Santos J, Gonçalves Cirino JP, de Oliveira Carvalho P, Ortega MM. The Pharmacological Action of Kaempferol in Central Nervous System Diseases: A Review. Front Pharmacol. 2021 Jan 13;11:565700. doi: 10.3389/fphar.2020.565700. eCollection 2020. PMID: 33519431; PMCID: PMC7838523.
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Front Pharmacol. 2021 Jan 13;11:565700. doi: 10.3389/fphar.2020.565700. eCollection 2020.

The Pharmacological Action of Kaempferol in Central Nervous System Diseases: A Review.

Frontiers in pharmacology

Jéssica Silva Dos Santos, João Pedro Gonçalves Cirino, Patrícia de Oliveira Carvalho, Manoela Marques Ortega

Affiliations

  1. Laboratory of Cell and Molecular Tumor Biology and Bioactive Compounds, Post Graduate Program in Health Science, São Francisco University (USF), Bragança Paulista, Brazil.
  2. Laboratory of Multidisciplinary Research, Post Graduate Program in Health Science, São Francisco University (USF), Bragança Paulista, Brazil.

PMID: 33519431 PMCID: PMC7838523 DOI: 10.3389/fphar.2020.565700

Abstract

Kaempferol (KPF) is a flavonoid antioxidant found in fruits and vegetables. Many studies have described the beneficial effects of dietary KPF in reducing the risk of chronic diseases, especially cancer. Nevertheless, little is known about the cellular and molecular mechanisms underlying KPF actions in the central nervous system (CNS). Also, the relationship between KPF structural properties and their glycosylation and the biological benefits of these compounds is unclear. The aim of this study was to review studies published in the PubMed database during the last 10 years (2010-2020), considering only experimental articles that addressed the isolated cell effect of KPF (C

Copyright © 2021 Silva dos Santos, Gonçalves Cirino, de Oliveira Carvalho and Ortega.

Keywords: Alzheimer; Parkinson; epilepsy; flavonoids; glioblastoma; ischemia stroke; kaempferol

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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