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Cancers (Basel). 2021 Jan 22;13(3). doi: 10.3390/cancers13030419.

Synthetic Cannabinoids Induce Autophagy and Mitochondrial Apoptotic Pathways in Human Glioblastoma Cells Independently of Deficiency in .

Cancers

Aleksandra Ellert-Miklaszewska, Iwona Anna Ciechomska, Bozena Kaminska

Affiliations

  1. Laboratory of Molecular Neurobiology, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 02-093 Warsaw, Poland.
  2. Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou 510095, China.

PMID: 33499365 PMCID: PMC7865605 DOI: 10.3390/cancers13030419

Abstract

Glioblastomas (GBMs) are aggressive brain tumors with frequent genetic alterations in

Keywords: PTEN; TP53; apoptosis; autophagy; cannabinoids; glioblastoma; mTOR; mitochondrial apoptotic pathway

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