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Emerg Radiol. 2021 Jun;28(3):497-505. doi: 10.1007/s10140-020-01886-y. Epub 2021 Feb 01.

Diagnosis of COVID-19 using CT scan images and deep learning techniques.

Emergency radiology

Vruddhi Shah, Rinkal Keniya, Akanksha Shridharani, Manav Punjabi, Jainam Shah, Ninad Mehendale

Affiliations

  1. K. J. Somaiya College of Engineering, Somaiya Vidyavihar University, Vidyavihar, Mumbai, 400077, India.
  2. K. J. Somaiya College of Engineering, Somaiya Vidyavihar University, Vidyavihar, Mumbai, 400077, India. [email protected].

PMID: 33523309 PMCID: PMC7848247 DOI: 10.1007/s10140-020-01886-y

Abstract

Early diagnosis of the coronavirus disease in 2019 (COVID-19) is essential for controlling this pandemic. COVID-19 has been spreading rapidly all over the world. There is no vaccine available for this virus yet. Fast and accurate COVID-19 screening is possible using computed tomography (CT) scan images. The deep learning techniques used in the proposed method is based on a convolutional neural network (CNN). Our manuscript focuses on differentiating the CT scan images of COVID-19 and non-COVID 19 CT using different deep learning techniques. A self-developed model named CTnet-10 was designed for the COVID-19 diagnosis, having an accuracy of 82.1%. Also, other models that we tested are DenseNet-169, VGG-16, ResNet-50, InceptionV3, and VGG-19. The VGG-19 proved to be superior with an accuracy of 94.52% as compared to all other deep learning models. Automated diagnosis of COVID-19 from the CT scan pictures can be used by the doctors as a quick and efficient method for COVID-19 screening.

Keywords: COVID-19; CT scan; Diagnosis using deep learning

References

  1. Wang C, Horby PW, Hayden FG, Gao GF (2020) A novel coronavirus outbreak of global health concern. Lancet 395(10223):470 - PubMed
  2. Wang LS, Wang YR, Ye DW, Liu QQ (2020) A review of the 2019 novel coronavirus (covid-19) based on current evidence. International journal of antimicrobial agents, 105948 - PubMed
  3. Singhal T (2020) A review of coronavirus disease-2019 (covid-19). The Indian Journal of Pediatrics, 1–6 - PubMed
  4. Wang R, Pan M, Zhang X, Han M, Fan X, Zhao F, Miao M, Xu J, Guan M, Deng X et al (2020) Epidemiological and clinical features of 125 hospitalized patients with covid-19 in Fuyang, Anhui, China. Int J Infect Dis 95:421 - PubMed
  5. Tang YW, Schmitz JE, Persing DH, Stratton CW (2020) Laboratory diagnosis of covid-19: current issues and challenges. J Clin Microbiol 58(6):512–520. https://doi.org/10.1128/JCM.00512-20 - PubMed
  6. Hussain A, Kaler J, Tabrez E, Tabrez S, Tabrez SS (2020) Novel covid-19: a comprehensive review of transmission, manifestation, and pathogenesis. Cureus 12(5):8184. https://doi.org/10.7759/cureus.8184 - PubMed
  7. Li B, Yang J, Zhao F, Zhi L, Wang X, Liu L, Bi Z, Zhao Y (2020) Prevalence and impact of cardiovascular metabolic diseases on covid-19 in China. Clin Res Cardiol 109(5):531 - PubMed
  8. Liu Z, Xiao X, Wei X, Li J, Yang J, Tan H, Zhu J, Zhang Q, Wu J, Liu L (2020) Composition and divergence of coronavirus spike proteins and host ace2 receptors predict potential intermediate hosts of sars-cov-2. J Med Virol 92(6):595 - PubMed
  9. Breban R, Riou J, Fontanet A (2013) Interhuman transmissibility of Middle East respiratory syndrome coronavirus: estimation of pandemic risk. Lancet 382(9893):694 - PubMed
  10. Ozturk T, Talo M, Yildirim EA, Baloglu UB, Yildirim O, Acharya UR (2020) Automated detection of covid-19 cases using deep neural networks with x-ray images. Computers in Biology and Medicine, 103792 - PubMed
  11. Singh D, Kumar V, Kaur M (2020) Classification of covid-19 patients from chest ct images using multi-objective differential evolution–based convolutional neural networks. European Journal of Clinical Microbiology & Infectious Diseases, 1–11 - PubMed
  12. Anjishnu Das SK (2020) Why covid testing is a slow process and types of tests available - PubMed
  13. Shen D, Wu G, Suk HI (2017) Deep learning in medical image analysis. Ann Rev Biomed Eng 19:221 - PubMed
  14. Ker J, Wang L, Rao J, Lim T (2017) Deep learning applications in medical image analysis. Ieee Access 6:9375 - PubMed
  15. Grewal M, Srivastava MM, Kumar P, Varadarajan S (2018) Radnet: Radiologist level accuracy using deep learning for hemorrhage detection in ct scans. In: IEEE 15th International symposium on biomedical imaging (ISBI 2018). IEEE, pp 281–284 - PubMed
  16. Song Q, Zhao L, Luo X, Dou X (2017) Using deep learning for classification of lung nodules on computed tomography images. Journal of healthcare engineering, 2017 - PubMed
  17. González G, Ash SY, Vegas-Sánchez-Ferrero G, Onieva Onieva J, Rahaghi FN, Ross JC, Díaz A, San José Estépar R, Washko GR (2018) Disease staging and prognosis in smokers using deep learning in chest computed tomography. Am J Respir Crit Care Med 197(2):193 - PubMed
  18. Ye Z, Zhang Y, Wang Y, Huang Z, Song B (2020) Chest ct manifestations of new coronavirus disease 2019 (covid-19): a pictorial review. European Radiology, 1–9 - PubMed
  19. Zhao W, Zhong Z, Xie X, Yu Q, Liu J (2020) Relation between chest CT findings and clinical conditions of coronavirus disease (covid-19) pneumonia: a multicenter study. Am J Roentgenol 214 (5):1072 - PubMed
  20. Bernheim A, Mei X, Huang M, Yang Y, Fayad ZA, Zhang N, Diao K, Lin B, Zhu X, Li K et al (2020) Chest CT findings in coronavirus disease-19 (covid-19): relationship to duration of infection. Radiology, 200463 - PubMed
  21. Zhao J, Zhang Y, He X, Xie P (2020) Covid-CT-dataset: a CT scan dataset about covid-19. arXiv: 2003.13865 - PubMed
  22. Gozes O, Frid-Adar M, Greenspan H, Browning PD, Zhang H, Ji W, Bernheim A, Siegel E (2020) Rapid ai development cycle for the coronavirus (covid-19) pandemic: initial results for automated detection & patient monitoring using deep learning ct image analysis. arXiv: 2003.05037 - PubMed
  23. Wu J, Wu X, Zeng W, Guo D, Fang Z, Chen L, Huang H, Li C (2020) Chest CT findings in patients with coronavirus disease 2019 and its relationship with clinical features. Investig Radiol 55 (5):257 - PubMed
  24. Zheng C, Deng X, Fu Q, Zhou Q, Feng J, Ma H, Liu W, Wang X (2020) Deep learning-based detection for covid-19 from chest CT using weak label, medRxiv - PubMed
  25. Ai T, Yang Z, Hou H, Zhan C, Chen C, Lv W, Tao Q, Sun Z, Xia L (2020) Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (covid-19) in China: a report of 1014 cases. Radiology, 200642 - PubMed
  26. Fang Y, Zhang H, Xie J, Lin M, Ying L, Pang P, Ji W (2020) Sensitivity of chest CT for covid-19: comparison to RT-PCR. Radiology, 200432 - PubMed
  27. Murphy K, Smits H, Knoops AJ, Korst MB, Samson T, Scholten ET, Schalekamp S, Schaefer-Prokop CM, Philipsen RH, Meijers A et al (2020) Covid-19 on the chest radiograph: a multi-reader evaluation of an AI system. Radiology, 201874 - PubMed
  28. Lee CI, Forman HP (2007) Ct screening for lung cancer: implications on social responsibility. Am J Roentgenol 188(2): 297 - PubMed

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