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Fernandes GMM, Galbiatti-Dias ALS, Ferreira LAM, et al. Anti-EGFR treatment effects on laryngeal cancer stem cells. Am J Transl Res. 2021;13(1):143-155
Fernandes, G. M. M., Galbiatti-Dias, A. L. S., Ferreira, L. A. M., Serafim Junior, V., Rodrigues-Fleming, G. H., de Oliveira-Cucolo, J. G., Biselli-Chicote, P. M., Kawasaki-Oyama, R. S., Maniglia, J. V., Pavarino, �. �. C., & Goloni-Bertollo, E. M. (2021). Anti-EGFR treatment effects on laryngeal cancer stem cells. American journal of translational research, 13(1), 143-155.
Fernandes, Glaucia Maria de Mendonça, et al. "Anti-EGFR treatment effects on laryngeal cancer stem cells." American journal of translational research vol. 13,1 (2021): 143-155.
Fernandes GMM, Galbiatti-Dias ALS, Ferreira LAM, Serafim Junior V, Rodrigues-Fleming GH, de Oliveira-Cucolo JG, Biselli-Chicote PM, Kawasaki-Oyama RS, Maniglia JV, Pavarino ÉC, Goloni-Bertollo EM. Anti-EGFR treatment effects on laryngeal cancer stem cells. Am J Transl Res. 2021 Jan 15;13(1):143-155. eCollection 2021. PMID: 33527014; PMCID: PMC7847503.
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Am J Transl Res. 2021 Jan 15;13(1):143-155. eCollection 2021.

Anti-EGFR treatment effects on laryngeal cancer stem cells.

American journal of translational research

Glaucia Maria de Mendonça Fernandes, Ana Lívia Silva Galbiatti-Dias, Leticia Antunes Muniz Ferreira, Vilson Serafim Junior, Gabriela Helena Rodrigues-Fleming, Juliana Garcia de Oliveira-Cucolo, Patrícia Matos Biselli-Chicote, Rosa Sayoko Kawasaki-Oyama, José Victor Maniglia, Érika Cristina Pavarino, Eny Maria Goloni-Bertollo

Affiliations

  1. Genetics and Molecular Biology Research Unit (UPGEM), São José do Rio Preto Medical School (FAMERP) São José do Rio Preto, São Paulo, Brazil.
  2. Department of Otolaryngology and Head and Neck Surgery, São José do Rio Preto Medical School (FAMERP) São José do Rio Preto, São Paulo, Brazil.

PMID: 33527014 PMCID: PMC7847503

Abstract

Laryngeal cancer (LC) is one of the common head and neck neoplasms and is characterized by resistance to conventional therapy and poor prognosis. This may result from the presence of cancer stem cells (CSCs), which form a small population in tumors with metastatic potential, high invasive capacity, self-renewal, and differentiation. This study aimed to evaluate the effectiveness of 5-fluorouracil and cisplatin individually, as well as the combination of cetuximab and paclitaxel in a CSC subpopulation separated with biomarkers related to tumoral growth (CD44, CD117, and CD133). In addition, expression of

AJTR Copyright © 2021.

Keywords: Cancer stem cells; cell line; chemotherapy; gene expression; head and neck neoplasms

Conflict of interest statement

None.

References

  1. Proc Jpn Acad Ser B Phys Biol Sci. 2017;93(3):146-154 - PubMed
  2. Mol Biol Cell. 2014 Sep 15;25(18):2677-81 - PubMed
  3. Oncogene. 2010 Apr 8;29(14):2047-59 - PubMed
  4. Methods Mol Biol. 2018;1692:31-42 - PubMed
  5. Pathol Res Pract. 2016 Jul;212(7):598-603 - PubMed
  6. Oncotarget. 2014 Mar 30;5(6):1491-501 - PubMed
  7. Int J Oncol. 2014 Dec;45(6):2439-45 - PubMed
  8. Nature. 2016 Jun 30;534(7609):647-51 - PubMed
  9. J Oral Pathol Med. 2018 Mar;47(3):221-227 - PubMed
  10. Stem Cell Rev Rep. 2018 Dec;14(6):769-784 - PubMed
  11. Oncol Rep. 2004 Feb;11(2):375-9 - PubMed
  12. J Natl Cancer Inst. 2016 Sep 15;109(1): - PubMed
  13. Head Neck. 2013 Oct;35(10):1507-14 - PubMed
  14. Cancer Res. 2005 Jul 1;65(13):5512-5 - PubMed
  15. FASEB J. 2013 Jan;27(1):13-24 - PubMed
  16. Nat Rev Drug Discov. 2014 Dec;13(12):928-42 - PubMed
  17. Oral Oncol. 2017 Oct;73:21-26 - PubMed
  18. Cancer Biol Ther. 2010 Sep 15;10(6):644-53 - PubMed
  19. Stem Cells Transl Med. 2014 Sep;3(9):1055-65 - PubMed
  20. PLoS One. 2012;7(9):e44071 - PubMed
  21. Front Oncol. 2017 Jun 02;7:112 - PubMed
  22. Med Sci Monit. 2018 Feb 05;24:727-735 - PubMed
  23. Cancer Res. 2016 Feb 15;76(4):767-8 - PubMed
  24. Oncol Lett. 2018 Aug;16(2):2105-2112 - PubMed
  25. Life Sci. 2017 Sep 1;184:25-29 - PubMed
  26. Am J Cancer Res. 2018 Aug 01;8(8):1633-1641 - PubMed
  27. Oncology. 2016;90(5):267-72 - PubMed
  28. Nature. 2011 May 19;473(7347):298-307 - PubMed
  29. BMC Cancer. 2013 Mar 18;13:125 - PubMed
  30. J Cell Physiol. 2018 Mar;233(3):2058-2066 - PubMed
  31. Sci Rep. 2015 Jan 15;5:7819 - PubMed
  32. Cancer Sci. 2010 May;101(5):1117-24 - PubMed
  33. Appl Immunohistochem Mol Morphol. 2005 Sep;13(3):205-20 - PubMed
  34. Cancer Res. 2006 Aug 15;66(16):7843-8 - PubMed
  35. ESMO Open. 2016 Mar 18;1(2):e000023 - PubMed
  36. Stem Cells Transl Med. 2017 Dec;6(12):2115-2125 - PubMed
  37. PLoS One. 2013 Sep 13;8(9):e75094 - PubMed
  38. Biochem Biophys Res Commun. 2018 Sep 10;503(3):1267-1272 - PubMed
  39. Indian J Cancer. 2014 Apr-Jun;51(2):89-94 - PubMed
  40. Int J Mol Sci. 2017 Apr 29;18(5): - PubMed
  41. PLoS One. 2014 Jun 24;9(6):e100944 - PubMed
  42. Oncotarget. 2016 Jul 26;7(30):47738-47749 - PubMed
  43. Clin Transl Oncol. 2017 Jun;19(6):769-776 - PubMed
  44. Cell Mol Biol (Noisy-le-grand). 2015 Oct 30;61(6):39-43 - PubMed
  45. Oncol Lett. 2019 Feb;17(2):2031-2039 - PubMed
  46. EMBO J. 2012 May 2;31(9):2103-16 - PubMed
  47. J Korean Med Sci. 2001 Aug;16(4):417-23 - PubMed
  48. PLoS One. 2012;7(1):e30246 - PubMed
  49. Cardiovasc Res. 2005 Feb 15;65(3):564-73 - PubMed
  50. Nat Methods. 2012 Jul;9(7):671-5 - PubMed
  51. Clin Exp Metastasis. 2013 Feb;30(2):165-76 - PubMed
  52. Arch Otolaryngol Head Neck Surg. 2006 Jul;132(7):771-8 - PubMed
  53. Indian J Cancer. 2017 Jan-Mar;54(1):20-24 - PubMed
  54. Int J Oral Maxillofac Surg. 2017 Feb;46(2):144-150 - PubMed
  55. Oncotarget. 2017 Mar 28;8(13):20961-20973 - PubMed

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