Infect Drug Resist. 2021 Feb 11;14:519-533. doi: 10.2147/IDR.S289964. eCollection 2021.
Knowledge, Attitudes, and Practices of Antimicrobial Uses and Resistance Among Public University Students in Bangladesh.
Infection and drug resistance
Mahfuza Marzan, Dewan Zubaer Islam, Halyna Lugova, Ambigga Krishnapillai, Mainul Haque, Salequl Islam
Affiliations
Affiliations
- Department of Microbiology, Jahangirnagar University, Savar, Dhaka, 1342, Bangladesh.
- The Unit of Community Medicine, Faculty of Medicine and Defence Health, National Defence University of Malaysia, Kuala Lumpur, 57000, Malaysia.
- The Unit of Family Medicine, Faculty of Medicine and Defence Health, National Defence University of Malaysia, Kuala Lumpur, 57000, Malaysia.
- The Unit of Pharmacology, Faculty of Medicine and Defence Health, Universiti Pertahanan Nasional Malaysia (National Defence University of Malaysia), Kuala Lumpur, 57000, Malaysia.
PMID: 33603416
PMCID: PMC7886243 DOI: 10.2147/IDR.S289964
Abstract
BACKGROUND: Antibiotics are lifesaving drugs, and inappropriate uses lead to the resistance that renders them ineffective. This study aims to understand knowledge, attitude, and practice (KAP) concerning antibiotic use and resistance among university students in Bangladesh.
METHODS: A cross-sectional study was performed from January to April 2020 among students at Jahangirnagar University (JU), Bangladesh. Purposive sampling was conducted through an in-person interview using a structured questionnaire. Students from the faculties of biological sciences and non-biology background were included. The univariate ordinal regression technique was used to analyze the relationship between predictors and good knowledge about the antibiotics. A two-tailed p-value was calculated to determine statistical association.
RESULTS: Out of 205 study participants, 92 and 113 responders were from biological science faculty and non-biology disciplines, respectively. Less than half of the students (42.4%) showed a good knowledge level (scores higher than 80%). Biology-background students possess better knowledge than non-biology students [odds ratio (OR) = 4.44, 95% confidence level (CL) (2.56, 7.70), p < 0.001]. A better attitude was noticed among all students. The self-medication rate was quite low, and more than 90% of students were found to consume antibiotics according to the physician's prescription. Lack of treatment adherence was recorded, and students admitted to stop-taking antibiotics when symptoms disappeared (48.67% biology and 36.26% non-biology). Multivariate regression analysis was unable to detect any significant association between self-medication and gender, student category or the level of knowledge about antibiotics.
CONCLUSION: Students of biological science background possessed better knowledge indicating the importance of appropriate curriculum imparted in knowledge buildup. Introducing a short course about the risk and development of antibiotic resistance will grow the students' awareness to avoid the resistance phenomenon.
© 2021 Marzan et al.
Keywords: Bangladesh; anti-bacterial agents; antibiotic; drug resistance; knowledge; state-owned; university students
Conflict of interest statement
The authors report no conflicts of interest for this work and declare that they do not have any financial involvement or affiliations with any organization, association, or entity directly or indirect
References
- Res Social Adm Pharm. 2020 Sep;16(9):1328-1329 - PubMed
- Int J Environ Res Public Health. 2020 Sep 05;17(18): - PubMed
- Expert Rev Anti Infect Ther. 2020 Dec 23;:1-5 - PubMed
- J Pharm Policy Pract. 2016 Oct 7;9:31 - PubMed
- BMC Res Notes. 2017 Jul 27;10(1):337 - PubMed
- BMC Infect Dis. 2018 Jul 6;18(1):312 - PubMed
- BMC Health Serv Res. 2017 Feb 13;17(1):136 - PubMed
- BMC Public Health. 2018 Jun 8;18(1):711 - PubMed
- Front Public Health. 2020 Nov 04;8:535668 - PubMed
- BMC Public Health. 2014 Aug 14;14:847 - PubMed
- Int J Environ Res Public Health. 2019 Oct 18;16(20): - PubMed
- Expert Rev Anti Infect Ther. 2019 Apr;17(4):275-284 - PubMed
- BMC Health Serv Res. 2018 Aug 31;18(1):676 - PubMed
- PLoS One. 2017 Feb 17;12(2):e0172146 - PubMed
- BMC Health Serv Res. 2020 Jul 15;20(1):656 - PubMed
- Indian J Dermatol. 2016 May-Jun;61(3):261-4 - PubMed
- Proc Natl Acad Sci U S A. 2011 Mar 15;108 Suppl 1:4554-61 - PubMed
- J Adv Nurs. 2016 Apr;72(4):946-57 - PubMed
- Ups J Med Sci. 2014 May;119(2):117-24 - PubMed
- Lancet Infect Dis. 2013 Dec;13(12):1057-98 - PubMed
- Int J Infect Dis. 2019 Mar;80:54-61 - PubMed
- BMC Public Health. 2018 Sep 24;18(1):1136 - PubMed
- BMJ Open. 2012 Jan 13;2:e000367 - PubMed
- PLoS One. 2019 Nov 22;14(11):e0225270 - PubMed
- BMC Med Educ. 2013 Dec 09;13:163 - PubMed
- Res Social Adm Pharm. 2008 Jun;4(2):164-72 - PubMed
- Behav Res Methods. 2017 Dec;49(6):2173-2181 - PubMed
- Int J Antimicrob Agents. 2001 Mar;17(3):171-6 - PubMed
- PLoS One. 2020 Jan 27;15(1):e0227947 - PubMed
- Glob Health Action. 2019 Dec 13;12(sup1):1824383 - PubMed
- Saudi J Biol Sci. 2017 May;24(4):808-812 - PubMed
- J Prim Care Community Health. 2020 Jan-Dec;11:2150132720961255 - PubMed
- Science. 2014 Nov 21;346(6212):954-9 - PubMed
- Risk Manag Healthc Policy. 2020 May 18;13:409-426 - PubMed
- J Palliat Med. 2009 Jan;12(1):77-82 - PubMed
- Health Serv Res. 2007 Jun;42(3 Pt 1):1219-34 - PubMed
- Curr Opin Pharmacol. 2014 Oct;18:56-60 - PubMed
- Public Health Rep. 2012 Jan-Feb;127(1):4-22 - PubMed
- Curr Opin Microbiol. 2019 Oct;51:72-80 - PubMed
- BMC Public Health. 2019 Jun 10;19(1):726 - PubMed
- Emerg Med J. 2003 Jan;20(1):54-60 - PubMed
- BMC Public Health. 2019 May 10;19(Suppl 3):498 - PubMed
- BMC Public Health. 2020 Dec 4;20(1):1861 - PubMed
- J Pharm Bioallied Sci. 2020 Apr-Jun;12(2):83-93 - PubMed
- BMJ. 2017 Sep 5;358:j3393 - PubMed
- PLoS One. 2013;8(2):e55495 - PubMed
- J Clin Diagn Res. 2015 Dec;9(12):FC17-22 - PubMed
- Int J Environ Res Public Health. 2018 Jun 04;15(6): - PubMed
- Microbiol Mol Biol Rev. 2010 Sep;74(3):417-33 - PubMed
- J Antimicrob Chemother. 2004 Oct;54(4):846-7 - PubMed
- Int J Antimicrob Agents. 2018 Dec;52(6):771-782 - PubMed
- Infect Drug Resist. 2019 May 17;12:1333-1351 - PubMed
- Antimicrob Resist Infect Control. 2017 May 15;6:47 - PubMed
- Expert Rev Anti Infect Ther. 2020 Dec 17;:1-8 - PubMed
- BMC Public Health. 2015 Aug 01;15:742 - PubMed
- J Pharm Policy Pract. 2020 Jun 3;13:20 - PubMed
- BMC Med Res Methodol. 2019 Mar 20;19(1):65 - PubMed
- Malawi Med J. 2019 Jun;31(2):133-137 - PubMed
- P T. 2015 Apr;40(4):277-83 - PubMed
- PLoS One. 2019 Feb 28;14(2):e0212875 - PubMed
- Lancet. 2019 Jan 12;393(10167):183-198 - PubMed
- Trends Microbiol. 2018 Dec;26(12):978-985 - PubMed
- BMC Med Res Methodol. 2019 Apr 2;19(1):73 - PubMed
- Public Health. 2019 Mar;168:92-101 - PubMed
- J Pers Soc Psychol. 2005 May;88(5):749-69 - PubMed
- BMC Public Health. 2019 May 6;19(1):518 - PubMed
- Antibiotics (Basel). 2019 Sep 19;8(3): - PubMed
- Am J Pharm Educ. 2008 Apr 15;72(2):43 - PubMed
- Can Pharm J (Ott). 2017 Oct 05;150(6):349-350 - PubMed
- Integr Pharm Res Pract. 2020 Feb 13;9:41-48 - PubMed
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